Ethical conduct of science, good governance of data, and accelerated translation to the clinic are key to high-calibre open neuroscience. Everyday practitioners of science must be sensitized to a range of ethical considerations in their research, some having especially to do with open data-sharing. The lessons included in this course introduce a number of these topics and end with concrete guidance for participant consent and de-identification of data.
A number of programming languages are ubiquitous in modern neuroscience and are key to the competence, freedom, and creativity necessary in neuroscience research. This course offers lectures on the fundamentals of data science and specific neuroinformatic tools used in the investigation of brain data. Attendees of this course will be learn about the programming languages Python, R, and MATLAB, as well as their associated packages and software environments.
There is a broad consensus among researchers, publishers, and funding bodies that open sharing of data is needed to address major reproducibility and transparency challenges that currently exist in all scientific disciplines. In addition to potentially increasing the utilization of shared data through re-analysis and integration with other data, data sharing is beneficial for individual researchers through data citation and increased exposure of research.
This course consists of one lesson and one tutorial, focusing on the neural connectivity measures derived from neuroimaging, specifically from methods like functional magnetic resonance imaging (fMRI) and diffusion-weighted imaging (DWI). Additional tools such as tractography and parcellation are discussed in the context of brain connectivity and mental health. The tutorial leads participants through the computation of brain connectomes from fMRI data.
Notebook systems are proving invaluable to skill acquisition, research documentation, publication, and reproducibility. This series of presentations introduces the most popular platform for computational notebooks, Project Jupyter, as well as other resources like Binder and NeuroLibre.
Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools.
This course tackles the issue of maintaining ethical research and healthcare practices in the age of increasingly powerful technological tools like machine learning and artificial intelligence. While there is great potential for innovation and improvement in the clinical space thanks to AI development, lecturers in this course advocate for a greater emphasis on human-centric care, calling for algorithm design which takes the full intersectionality of individuals into account.
The goal of this module is to work with action potential data taken from a publicly available database. You will learn about spike counts, orientation tuning, and spatial maps. The MATLAB code introduces data types, for-loops and vectorizations, indexing, and data visualization.
This course is intended for those interested in electroencephalography (EEG) and event-related potentials (ERPs) techniques, and those interested in collecting, annotating, standardizing, storing, processing, sharing, and publishing data from electrical activity of the human brain.
The importance of Research Data Management in the conduct of open and reproducible science is better understood and technically supported than ever, and many of the underlying principles apply as much to everyday activities of a single researcher as to large-scale, multi-center open data sharing.
Get up to speed about the fundamental principles of full brain network modeling using the open-source neuroinformatics platform The Virtual Brain (TVB). This simulation environment enables the biologically realistic modeling of whole-brain network dynamics across different brain scales, using personalized structural connectome-based approach.
This module covers fMRI data, including creating and interpreting flatmaps, exploring variability and average responses, and visual eccenticity. You will learn about processing BOLD signals, trial-averaging, and t-tests. The MATLAB code introduces data animations, multicolor visualizations, and linear indexing.
This course is intended to introduce researchers to the Open Science Framework (OSF). OSF is a free, open source web application built by the Center for Open Science, a non-profit dedicated to improving the alignment between scientific values and scientific practices. OSF is part collaboration tool, part version control software, and part data archive.
Difficulties experienced in understanding machine learning techniques often stem from lack of clarity concerning more basic statistical models and fundamental considerations, including the various regression models that can all be subsumed under the General Linear Model.
The Neurodata Without Borders: Neurophysiology project (NWB, https://www.nwb.org/) is an effort to standardize the description and storage of neurophysiology data and metadata. NWB enables data sharing and reuse and reduces the energy-barrier to applying data analytics both within and across labs. Several laboratories, including the Allen Institute for Brain Science, have wholeheartedly adopted NWB.
This course corresponds to the third session of talks given at INCF's Neuroinformatics Assembly 2023. In this session, the talks revolve around the idea of cross-platform data integration, discussing processes and solutions for rapidly developing an integrated workflow across independent systems for the US BRAIN Initiative Cell Census.