This course contains sessions from the second day of INCF's Neuroinformatics Assembly 2022.

This working group is a collaboration between OCNS and INCF. The group focuses on evaluating and testing computational neuroscience tools; finding them, testing them, learning how they work, and informing developers of issues to ensure that these tools remain in good shape by having communities looking after them. Since many members of the WG are themselves tool developers, we will also learn from each other and will work towards improving interoperability between related tools.

As research methods and experimental technologies become ever more sophisticated, the amount of health-related data per individual which has become accessible is vast, giving rise to a corresponding need for cross-domain data integration, whole-person modelling, and improved precision medicine. This course provides lessons describing state of the art methods and repositories, as well as a tutorial on computational methods for data integration. 

This course provides a broad, non-technical overview of the field of neurotechnology. It is intended to provide users with a fundamental understanding of how neurotechnology works.

This course offers lectures on the origin and functional significance of certain electrophysiological signals in the brain, as well as a hands-on tutorial on how to simulate, statistically evaluate, and visualize such signals. Participants will learn the simulation of signals at different spatial scales, including single-cell (neuronal spiking) and global (EEG), and how these may serve as biomarkers in the evaluation of mental health data.

Over the last three decades, neuroimaging research has seen large strides in the scale, diversity, and complexity of studies, the open availability of data and methodological resources, the quality of instrumentation and multimodal studies, and the number of researchers and consortia. The awareness of rigor and reproducibility has increased with the advent of funding mandates, and with the work done by national and international brain initiatives.

This workshop is organized by the German National Research Data Infrastructure Initiative Neuroscience (NFDI-Neuro). The initiative is community driven and comprises around 50 contributing national partners and collaborators. NFDI-Neuro partners with EBRAINS AISB, the coordinating entity of the EU Human Brain Project and the EBRAINS infrastructure. We will introduce common methods that enable digital reproducible neuroscience.

This workshop hosted by HBP, EBRAINS, and the European Academy of Neurology (EAN) aimed to identify and openly discuss all issues and challenges associated with data sharing in Europe: from ethics to data safety and privacy including those specific to data federation such as the development and validation of federated algorithms. 

Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.

This course consists of one lesson and one tutorial, focusing on the neural connectivity measures derived from neuroimaging, specifically from methods like functional magnetic resonance imaging (fMRI) and diffusion-weighted imaging (DWI). Additional tools such as tractography and parcellation are discussed in the context of brain connectivity and mental health. The tutorial leads participants through the computation of brain connectomes from fMRI data. 

Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools.

The course provides an introduction to the growing field of electrophysiology standards, infrastructure, and initiatives. From data curation on open research infrastructures like EBRAINS, to overviews of national data analytics platforms like Australia's AEDAPT, the lessons in this course highlight already available resources for the global neuroinformatics commuity while also reinforcing the need for and importance of FAIR science principles in future research projects.

As technological improvements continue to facilitate innovations in the mental health space, researchers and clinicians are faced with novel opportunities and challenges regarding study design, diagnoses, treatments, and follow-up care. This course includes a lecture outlining these new developments, as well as a workshop which introduces users to Synapse, an open-source platform for collaborative data analysis. 

Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.

Bayesian inference (using prior knowledge to generate more accurate predictions about future events or outcomes) has become increasingly applied to the fields of neuroscience and neuroinformatics. In this course, participants are taught how Bayesian statistics may be used to build cognitive models of processes like learning or perception. This course also offers theoretical and practical instruction on dynamic causal modeling as applied to fMRI and EEG data.

In this course, you will learn how computational neuroscientists use mathematical models and computer simulations to study different plasticity phenomena in the brain. During the course, you will program your own neuron model, a so-called leaky-integrate-and-fire (LIF) neuron model, and simulate it with a computer. You will also learn how to add various neuronal properties and plasticity mechanisms to the model and study how they operate.

This course, arranged by EPFL and also available as a MOOC on edX, aims for a mechanistic description of mammalian brain function at the level of individual nerve cells and their synaptic interactions.

The Neurodata Without Borders: Neurophysiology project (NWB, https://www.nwb.org/) is an effort to standardize the description and storage of neurophysiology data and metadata. NWB enables data sharing and reuse and reduces the energy-barrier to applying data analytics both within and across labs. Several laboratories, including the Allen Institute for Brain Science, have wholeheartedly adopted NWB.

This workshop provides basic knowledge on personalized brain network modeling using the open-source simulation platform The Virtual Brain (TVB). Participants will gain theoretical knowledge and apply this knowledge to construct brain models, process multimodal neuroimaging data for reconstructing individual brains, run simulations, and use supporting neuroinformatics tools such as collaboratories, pipelines, workflows, and data repositories.

Ethical conduct of science, good governance of data, and accelerated translation to the clinic are key to high-calibre open neuroscience.  Everyday practitioners of science must be sensitized to a range of ethical considerations in their research, some having especially to do with open data-sharing. The lessons included in this course introduce a number of these topics and end with concrete guidance for participant consent and de-identification of data.