Sessions from the INCF Neuroinformatics Assembly 2022 day 2. 

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There is a broad consensus among researchers, publishers, and funding bodies that open sharing of data is needed to address major reproducibility and transparency challenges that currently exist in all scientific disciplines. In addition to potentially increasing the utilization of shared data through re-analysis and integration with other data, data sharing is beneficial for individual researchers through data citation and increased exposure of research.

Probing the organization of interactions within and across neuronal populations is a promising approach to understanding the principles of brain processing. The rapidly advancing technical capabilities to record from hundreds of neurons in parallel open up new possibilities to disentangle the correlative structure within neuronal networks. However, the complexity of these massive data streams calls for novel, tractable analysis tools that exploit the parallel aspect of the data.

A number of programming languages are ubiquitous in modern neuroscience and are key to the competence, freedom, and creativity necessary in neuroscience research. This course offers lectures on the fundamentals of data science and specific neuroinformatic tools used in the investigation of brain data. Attendees of this course will be learn about the programming languages Python, R, and MATLAB, as well as their associated packages and software environments. 

Neuroanatomy provides one of the unifying frameworks for neuroscience and thus it is not surprising that it provides the basis for many neuroinformatics tools and approaches.  Regardless of whether one is working at the subcellular, cellular or gross anatomical level or whether one is modeling circuitry, molecular pathways or function, at some point, this work will include an anatomical reference.

Most approaches within computational neuroscience simulate systems, brain networks, local circuits, as they are now. In recent years, homeostatic regulation has been characterized and modeled; however, for understanding diseases that have their origin in genetic defects that emerge at later age, it is important to understand how these defects interact with developmental processes that occur earlier and last longer that the typical period considered for homeostatic studies.

As technological improvements continue to facilitate innovations in the mental health space, researchers and clinicians are faced with novel opportunities and challenges regarding study design, diagnoses, treatments, and follow-up care. This course includes a lecture outlining these new developments, as well as a workshop which introduces users to Synapse, an open-source platform for collaborative data analysis. 

This course offers lectures on the origin and functional significance of certain electrophysiological signals in the brain, as well as a hands-on tutorial on how to simulate, statistically evaluate, and visualize such signals. Participants will learn the simulation of signals at different spatial scales, including single-cell (neuronal spiking) and global (EEG), and how these may serve as biomarkers in the evaluation of mental health data.

A virtual workshop with lectures and hands-on tutorials that will teach participants how to use open-source Miniscopes for in vivo calcium imaging. This workshop is designed to introduce all aspects of using Miniscopes, including basic principles of Miniscope design and imaging, how to build and attach a Miniscope, how to implant a GRIN lens for imaging deep structures, and how to analyze imaging data.

This course corresponds to the third session of talks given at INCF's Neuroinformatics Assembly 2023. In this session, the talks revolve around the idea of cross-platform data integration, discussing processes and solutions for rapidly developing an integrated workflow across independent systems for the US BRAIN Initiative Cell Census. 

EEGLAB is an interactive MATLAB toolbox for processing continuous and event-related EEG, MEG, and other electrophysiological data. In this course, you will learn about features incorporated into EEGLAB, including independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data. EEGLAB runs under Linux, Unix, Windows, and Mac OS X.

This course contains sessions from the second day of INCF's Neuroinformatics Assembly 2022.

Standards and best practices make neuroscience a data-centric discipline and are key for integrating diverse data and for developing a robust, effective, and sustainable infrastructure to support open and reproducible neuroscience. This study track provides an introduction to standards and best practices that support the FAIR Principles.

This course corresponds to the second session of INCF's Neuroinformatics Assembly 2023. This series of talks continues a discussion of FAIR principles from the first session, with a greater emphasis on brain data (humans and animals) atlases for data analysis and integation. 

In this short series of lectures, participants will take a look at articles using TVB in a clinical context. Specifically, participants will see how TVB can help to predict recovery after stroke and how individual epileptic seizures are simulated. The course lecturers will briefly describe the methods used and results achieved in the articles.

There is a growing recognition and adoption of open and FAIR science practices in neuroscience research. This is predominately regarded as scientific progress and has enabled significant opportunities for large, collaborative, team science. The efforts and practical work that go into creating an open and FAIR landscape extend far beyond just the science.

There is a growing recognition and adoption of open and FAIR science practices in neuroscience research. This is predominately regarded as scientific progress and has enabled significant opportunities for large, collaborative, team science. The efforts and practical work that go into creating an open and FAIR landscape extend far beyond just the science.

The emergence of data-intensive science creates a demand for neuroscience educators worldwide to deliver better neuroinformatics education and training in order to raise a generation of modern neuroscientists with FAIR capabilities, awareness of the value of standards and best practices, knowledge in dealing with big datasets, and the ability to integrate knowledge over multiple scales and methods.

Since their introduction in 2016, the FAIR data principles have gained increasing recognition and adoption in global neuroscience. FAIR defines a set of high level principles and practices for making digital objects, including data, software and workflows, Findable, Accessible, Interoperable and Reusable. But FAIR is not a specification; it leaves many of the specifics up to individual scientific disciplines to define.

Given the extreme interconnectedness of the human brain, studying any one cerebral area in isolation may lead to spurious results or incomplete, if not problematic, interpretations. This course introduces participants to the various spatial scales of neuroscience and the fundamentals of whole-brain modelling, used to generate a more thorough picture of brain activity.