This course corresponds to the first session of talks given at INCF's Neuroinformatics Assembly 2023. The sessions consists of several lectures, focusing on using the principles of FAIR (findability, accessibility, interoperability, and reusability) to inform future directions in neuroscience and neuroinformatics. In particular, these talks deal with the development of knowledge graphs and ontologies.
This course is currently under construction but will coming soon. It will give an overview of the world of scientific publishing, spanning from traditional formats, to open to access, to open, interactive, reproducible, and 'living' publications with modifiable and executable code.
This course consists of two workshops which focus on the need for reproducibility in science, particularly under the umbrella roadmap of FAIR scienctific principles. The tutorials also provide an introduction to some of the most commonly used open-source scientific tools, including Git, GitHub, Google Colab, Binder, Docker, and the programming languages Python and R.
In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.
Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.
This course contains videos, lectures, and hands-on tutorials as part of INCF's Neuroinformatics Assembly 2023 workshop on developing robust and reproducible research workflows to foster greater collaborative efforts in neuroscience.
The emergence of data-intensive science creates a demand for neuroscience educators worldwide to deliver better neuroinformatics education and training in order to raise a generation of modern neuroscientists with FAIR capabilities, awareness of the value of standards and best practices, knowledge in dealing with big datasets, and the ability to integrate knowledge over multiple scales and methods.
Most who enter the field of computational neuroscience have a prior background in either mathematics, physics, computer science, or (neuro)biology. Since computational neuroscience requires a bit of knowledge from all these fields, with some basic knowledge of neurons and a familiarity with certain types of equations and mathematical concepts, we recommend two different "starting tracks" depending on the student's background before you begin the lectures listed below:
This course consists of introductory lectures on different aspects of biochemical models. By following this course, you will learn about the various forms plasticity can take at different levels in the brain, how to model chemical computation in the brain, as well as computationally demanding studies of synaptic plasticity on the molecular level.
This course offers lectures on the origin and functional significance of certain electrophysiological signals in the brain, as well as a hands-on tutorial on how to simulate, statistically evaluate, and visualize such signals. Participants will learn the simulation of signals at different spatial scales, including single-cell (neuronal spiking) and global (EEG), and how these may serve as biomarkers in the evaluation of mental health data.
Sessions from the INCF Neuroinformatics Assembly 2022 day 2.
This course contains sessions from the second day of INCF's Neuroinformatics Assembly 2022.
This course contains sessions from the first day of INCF's Neuroinformatics Assembly 2022.
Bayesian inference (using prior knowledge to generate more accurate predictions about future events or outcomes) has become increasingly applied to the fields of neuroscience and neuroinformatics. In this course, participants are taught how Bayesian statistics may be used to build cognitive models of processes like learning or perception. This course also offers theoretical and practical instruction on dynamic causal modeling as applied to fMRI and EEG data.
This module covers fMRI data, including creating and interpreting flatmaps, exploring variability and average responses, and visual eccenticity. You will learn about processing BOLD signals, trial-averaging, and t-tests. The MATLAB code introduces data animations, multicolor visualizations, and linear indexing.
The dimensionality and size of datasets in many fields of neuroscience research require massively parallel computing power. Fortunately, the maturity and accessibility of virtualization technologies has made it feasible to run the same analysis environments on platforms ranging from single laptop computers up to high-performance computing networks.
This course includes both lectures and tutorials around the management and analysis of genomic data in clinical research and care. Participants are led through the basics of genome-wide association studies (GWAS), genotypes, and polygenic risk scores, as well as novel concepts and tools for more sophisticated consideration of population stratification in GWAS.
As research methods and experimental technologies become ever more sophisticated, the amount of health-related data per individual which has become accessible is vast, giving rise to a corresponding need for cross-domain data integration, whole-person modelling, and improved precision medicine. This course provides lessons describing state of the art methods and repositories, as well as a tutorial on computational methods for data integration.
EEGLAB is an interactive MATLAB toolbox for processing continuous and event-related EEG, MEG, and other electrophysiological data. In this course, you will learn about features incorporated into EEGLAB, including independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data. EEGLAB runs under Linux, Unix, Windows, and Mac OS X.
The goal of this module is to work with action potential data taken from a publicly available database. You will learn about spike counts, orientation tuning, and spatial maps. The MATLAB code introduces data types, for-loops and vectorizations, indexing, and data visualization.