This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?
This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases.
This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.
This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system.
This lecture covers the ethical implications of the use of pharmaceuticals to enhance brain functions and was part of the Neuro Day Workshop held by the NeuroSchool of Aix Marseille University.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
In this lesson, you will hear about the current challenges regarding data management, as well as policies and resources aimed to address them.
This lecture covers the NIDM data format within BIDS to make your datasets more searchable, and how to optimize your dataset searches.
This lecture covers positron emission tomography (PET) imaging and the Brain Imaging Data Structure (BIDS), and how they work together within the PET-BIDS standard to make neuroscience more open and FAIR.
This lecture contains an overview of electrophysiology data reuse within the EBRAINS ecosystem.
This lecture contains an overview of the Distributed Archives for Neurophysiology Data Integration (DANDI) archive, its ties to FAIR and open-source, integrations with other programs, and upcoming features.
This lecture discusses how to standardize electrophysiology data organization to move towards being more FAIR.
This session discussed the secret life of your dataset metadata: the ways in which, for many years to come, it will work non-stop to foster the visibility, reach, and impact of your work. We explored how metadata will help your dataset travel through the global research infrastructure, and how data repositories and discovery services can use this metadata to help launch your dataset into the world.
This lesson provides information on developing data management plans (DMPs), including an overview of how DMPs contribute to effective research efforts, as well as specific development resources and DMP examples.
In this session, participants will take an in-depth look at the newly launched DMP Assistant 2.0, including all of its enhanced key features for both end-users and institutional administrators, as well as a brief look at the future of the platform.
This lecture discusses differential privacy and synthetic data in the context of medical data sharing in clinical neurosciences.
This talk presents state-of-the-art methods for ensuring data privacy with a particular focus on medical data sharing across multiple organizations.
This lesson discusses the need for and approaches to integrating data across the various temporal and spatial scales in which brain activity can be measured.
This lesson consists of lecture and tutorial components, focusing on resources and tools which facilitate multi-scale brain modeling and simulation.