The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
In this lesson, while learning about the need for increased large-scale collaborative science that is transparent in nature, users also are given a tutorial on using Synapse for facilitating reusable and reproducible research.
This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling.
Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.
This lesson provides an introduction the International Neuroinformatics Coordinating Facility (INCF), its mission towards FAIR neuroscience, and future directions.
This brief video provides an introduction to the third session of INCF's Neuroinformatics Assembly 2023, focusing on how to streamling cross-platform data integration in a neuroscientific context.
This final lesson of the course consists of the panel discussion for Streamlining Cross-Platform Data Integration session during the first day of INCF's Neuroinformatics Assembly 2023.
This lightning talk describes the heterogeneity of the MR field regarding types of scanners, data formats, protocols, and software/hardware versions, as well as the challenges and opportunities for unifying these datasets in a common interface, MRdataset.
This session covers the framework of the International Brain Lab (IBL) and the data architecture used for this project.
This lecture provides an introduction to the study of eye-tracking in humans.
From the retina to the superior colliculus, the lateral geniculate nucleus into primary visual cortex and beyond, this lecture gives a tour of the mammalian visual system highlighting the Nobel-prize winning discoveries of Hubel & Wiesel.
From Universal Turing Machines to McCulloch-Pitts and Hopfield associative memory networks, this lecture explains what is meant by computation.
In an overview of the structure of the mammalian neocortex, this lecture explains how the mammalian cortex is organized in a hierarchy, describing the columnar principle and canonical microcircuits.
The retina has 60 different types of neurons. What are their functions? This lecture explores the definition of cell types and their functions in the mammalian retina.
Optical imaging offers a look inside the working brain. This lecture takes a look at orientation and ocular dominance columns in the visual cortex, and shows how they can be viewed with calcium imaging.
Functional imaging has led to the discovery of a plethora of visual cortical regions. This lecture introduces functional imaging techniques and their teachings about the visual cortex.
This lecture explains these ideas and explores the task of characterizing neuronal response properties using information theory.
What is color? This lecture explores how color is "made" in the brain and variations of color perception including trichromacy, color blindness in men, tetrachromatic vision in women, and genetic engineering of color perception.
How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.
What is the difference between attention and consciousness? This lecture describes the scientific meaning of consciousness, journeys on the search for neural correlates of visual consciousness, and explores the possibility of consciousness in other beings and even non-biological structures.