Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation. 

In this lesson you will learn how machine learners and neuroscientists construct abstract computational models based on various neurophysiological signalling properties. 

This lesson introduces some practical exercises which accompany the Synapses and Networks portion of this Neuroscience for Machine Learners course. 

This lesson delves into the human nervous system and the immense cellular, connectomic, and functional sophistication therein. 

This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

 In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way. 

In this lesson, you will learn how to train spiking neural networks (SNNs) with a surrogate gradient method. 

In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

Explore how to setup an epileptic seizure simulation with the TVB graphical user interface. This lesson will show you how to program the epileptor model in the brain network to simulate a epileptic seizure originating in the hippocampus. It will also show how to upload and view mouse connectivity data, as well as give a short introduction to the python script interface of TVB.

Brain network reconstruction from empirical data is of key importance to generate personalized virtual brain models. This lecture will introduce the basic concepts of preprocessing structural, functional and diffusion weighted neuroimages. It highlights the latest methods and pipelines to extract structural as well as functional connectomes according to a multimodal parcellation.

This lecture presents two recent clinical case studies using TVB: stroke recovery and dementia (due to Alzheimer’s Disease (AD)). Using a multi-scale neurophysiological model based on empirical multi-modal neuroimaging data, we show how local and global biophysical parameters characterize changes in individualized patient-specific brain dynamics, predict recovery of motor function for stroke patients, and correlate with individual differences in cognition for AD patients.

This tutorial provides instruction on how to simulate brain tumors with TVB (reproducing publication: Marinazzo et al. 2020 Neuroimage). This tutorial comprises a didactic video, jupyter notebooks, and full data set for the construction of virtual brains from patients and health controls.

The tutorial on modelling strokes in TVB includes a didactic video and jupyter notebooks (reproducing publication: Falcon et al. 2016 eNeuro).

This lesson gives an overview of the Brainstorm package for analyzing extracellular electrophysiology, including preprocessing, spike sorting, trial alignment, and spectrotemporal decomposition.

This lesson provides an overview of the CaImAn package, as well as a demonstration of usage with NWB.

This lesson gives an overview of the SpikeInterface package, including demonstration of data loading, preprocessing, spike sorting, and comparison of spike sorters.

In this lesson, users will learn about the NWBWidgets package, including coverage of different data types, and information for building custom widgets within this framework.

This lesson introduces population models and the phase plane, and is part of the The Virtual Brain (TVB) Node 10 Series, a 4-day workshop dedicated to learning about the full brain simulation platform TVB, as well as brain imaging, brain simulation, personalised brain models, and TVB use cases.