The landscape of scientific research is changing. Today’s researchers need to participate in large-scale collaborations, obtain and manage funding, share data, publish, and undertake knowledge translation activities in order to be successful. As per these increasing demands, Science Management is now a vital piece of the environment. This course consists of lectures presenting practical techniques, tools, and project management skills that participants can begin to implement.
This course tackles the issue of maintaining ethical research and healthcare practices in the age of increasingly powerful technological tools like machine learning and artificial intelligence. While there is great potential for innovation and improvement in the clinical space thanks to AI development, lecturers in this course advocate for a greater emphasis on human-centric care, calling for algorithm design which takes the full intersectionality of individuals into account.
The Neurodata Without Borders: Neurophysiology project (NWB, https://www.nwb.org/) is an effort to standardize the description and storage of neurophysiology data and metadata. NWB enables data sharing and reuse and reduces the energy-barrier to applying data analytics both within and across labs. Several laboratories, including the Allen Institute for Brain Science, have wholeheartedly adopted NWB.
This course consists of one lesson and one tutorial, focusing on the neural connectivity measures derived from neuroimaging, specifically from methods like functional magnetic resonance imaging (fMRI) and diffusion-weighted imaging (DWI). Additional tools such as tractography and parcellation are discussed in the context of brain connectivity and mental health. The tutorial leads participants through the computation of brain connectomes from fMRI data.
As technological improvements continue to facilitate innovations in the mental health space, researchers and clinicians are faced with novel opportunities and challenges regarding study design, diagnoses, treatments, and follow-up care. This course includes a lecture outlining these new developments, as well as a workshop which introduces users to Synapse, an open-source platform for collaborative data analysis.
In this course, you will learn how computational neuroscientists use mathematical models and computer simulations to study different plasticity phenomena in the brain. During the course, you will program your own neuron model, a so-called leaky-integrate-and-fire (LIF) neuron model, and simulate it with a computer. You will also learn how to add various neuronal properties and plasticity mechanisms to the model and study how they operate.
This couse is the opening module for the University of Toronto's Krembil Centre for Neuroinformatics' virtual learning series Solving Problems in Mental Health Using Multi-Scale Computational Neuroscience. Lessons in this course introduce participants to the study of brain disorders, starting from elemental units like genes and neurons, eventually building up to whole-brain modelling and global activity patterns.
This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression).
This module introduces computational neuroscience by simulating neurons according to the AdEx model. You will learn about generative modeling, dynamical systems, and F-I curves. The MATLAB code introduces live scripts and functions.
In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.
The International Brain Initiative (IBI) is a consortium of the world’s major large-scale brain initiatives and other organizations with a vested interest in catalyzing and advancing neuroscience research through international collaboration and knowledge sharing. This session will introduce the IBI and the current efforts of the Data Standards and Sharing Working Group with a view to gain input from a wider neuroscience and neuroinformatics community.
Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.
This course offers lectures on the origin and functional significance of certain electrophysiological signals in the brain, as well as a hands-on tutorial on how to simulate, statistically evaluate, and visualize such signals. Participants will learn the simulation of signals at different spatial scales, including single-cell (neuronal spiking) and global (EEG), and how these may serve as biomarkers in the evaluation of mental health data.
Sessions from the INCF Neuroinformatics Assembly 2022 day 2.
The lecture series focuses on current trends in modern techniques in neuroscience. Inspiring scientists from the NeurotechEU Alliance will give an overview of the latest advances and developments.
This course contains sessions from the second day of INCF's Neuroinformatics Assembly 2022.
Sessions from the INCF Neuroinformatics Assembly 2022 day 2.
The Virtual Brain EduPack provides didactic use cases for The Virtual Brain (TVB). Typically a use case consists of a jupyter notebook and a didactic video. EduPack use cases help the user to reproduce TVB-based publications or to get started quickly with TVB.
Get up to speed about the fundamental principles of full brain network modeling using the open-source neuroinformatics platform The Virtual Brain (TVB). This simulation environment enables the biologically realistic modeling of whole-brain network dynamics across different brain scales, using personalized structural connectome-based approach.
This course contains videos, lectures, and hands-on tutorials as part of INCF's Neuroinformatics Assembly 2023 workshop on developing robust and reproducible research workflows to foster greater collaborative efforts in neuroscience.