This lesson provides an overview of the database of Genotypes and Phenotypes (dbGaP), which was developed to archive and distribute the data and results from studies that have investigated the interaction of genotype and phenotype in humans.
This lightning talk describes an automated pipline for positron emission tomography (PET) data.
This session introduces the PET-to-BIDS (PET2BIDS) library, a toolkit designed to simplify the conversion and preparation of PET imaging datasets into BIDS-compliant formats. It supports multiple data types and formats (e.g., DICOM, ECAT7+, nifti, JSON), integrates seamlessly with Excel-based metadata, and provides automated routines for metadata updates, blood data conversion, and JSON synchronization. PET2BIDS improves human readability by mapping complex reconstruction names into standardized, descriptive labels and offers extensive documentation, examples, and video tutorials to make adoption easier for researchers.
This session introduces the PET-to-BIDS (PET2BIDS) library, a toolkit designed to simplify the conversion and preparation of PET imaging datasets into BIDS-compliant formats. It supports multiple data types and formats (e.g., DICOM, ECAT7+, nifti, JSON), integrates seamlessly with Excel-based metadata, and provides automated routines for metadata updates, blood data conversion, and JSON synchronization. PET2BIDS improves human readability by mapping complex reconstruction names into standardized, descriptive labels and offers extensive documentation, examples, and video tutorials to make adoption easier for researchers.
This session dives into practical PET tooling on BIDS data—showing how to run motion correction, register PET↔MRI, extract time–activity curves, and generate standardized PET-BIDS derivatives with clear QC reports. It introduces modular BIDS Apps (head-motion correction, TAC extraction), a full pipeline (PETPrep), and a PET/MRI defacer, with guidance on parameters, outputs, provenance, and why Dockerized containers are the reliable way to run them at scale.
This session introduces two PET quantification tools—bloodstream for processing arterial blood data and kinfitr for kinetic modeling and quantification—built to work with BIDS/BIDS-derivatives and containers. Bloodstream fuses autosampler and manual measurements (whole blood, plasma, parent fraction) using interpolation or fitted models (incl. hierarchical GAMs) to produce a clean arterial input function (AIF) and whole-blood curves with rich QC reports ready. TAC data (e.g., from PETPrep) and blood (e.g., from bloodstream) can be ingested using kinfitr to run reproducible, GUI-driven analyses: define combined ROIs, calculate weighting factors, estimate blood–tissue delay, choose and chain models (e.g., 2TCM → 1TCM with parameter inheritance), and export parameters/diagnostics. Both are available as Docker apps; workflows emphasize configuration files, reports, and standard outputs to support transparency and reuse.
This lecture covers positron emission tomography (PET) imaging and the Brain Imaging Data Structure (BIDS), and how they work together within the PET-BIDS standard to make neuroscience more open and FAIR.
This module covers many of the types of non-invasive neurotech and neuroimaging devices including electroencephalography (EEG), electromyography (EMG), electroneurography (ENG), magnetoencephalography (MEG), and more.
This lecture explains the concept of federated analysis in the context of medical data, associated challenges. The lecture also presents an example of hospital federations via the Medical Informatics Platform.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat.
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
This is a tutorial on how to simulate neuronal spiking in brain microcircuit models, as well as how to analyze, plot, and visualize the corresponding data.
Maximize Your Research With Cloud Workspaces is a talk aimed at researchers who are looking for innovative ways to set up and execute their life science data analyses in a collaborative, extensible, open-source cloud environment. This panel discussion is brought to you by MetaCell and scientists from leading universities who share their experiences of advanced analysis and collaborative learning through the Cloud.
This talk describes the relevance and power of using brain atlases as part of one's data integration pipeline.
In this third and final hands-on tutorial from the Research Workflows for Collaborative Neuroscience workshop, you will learn about workflow orchestration using open source tools like DataJoint and Flyte.