PET-BIDS Tool Demonstrations and Tutorials: Quantification

This session introduces two PET quantification tools—bloodstream for processing arterial blood data and kinfitr for kinetic modeling and quantification—built to work with BIDS/BIDS-derivatives and containers. Bloodstream fuses autosampler and manual measurements (whole blood, plasma, parent fraction) using interpolation or fitted models (incl. hierarchical GAMs) to produce a clean arterial input function (AIF) and whole-blood curves with rich QC reports ready. TAC data (e.g., from PETPrep) and blood (e.g., from bloodstream) can be ingested using kinfitr to run reproducible, GUI-driven analyses: define combined ROIs, calculate weighting factors, estimate blood–tissue delay, choose and chain models (e.g., 2TCM → 1TCM with parameter inheritance), and export parameters/diagnostics. Both are available as Docker apps; workflows emphasize configuration files, reports, and standard outputs to support transparency and reuse.