In this lesson, while learning about the need for increased large-scale collaborative science that is transparent in nature, users also are given a tutorial on using Synapse for facilitating reusable and reproducible research. 

This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling. 

Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.

This lesson provides an introduction the International Neuroinformatics Coordinating Facility (INCF), its mission towards FAIR neuroscience, and future directions. 

This brief video provides an introduction to the third session of INCF's Neuroinformatics Assembly 2023, focusing on how to streamling cross-platform data integration in a neuroscientific context. 

This final lesson of the course consists of the panel discussion for Streamlining Cross-Platform Data Integration session during the first day of INCF's Neuroinformatics Assembly 2023. 

This lightning talk describes the heterogeneity of the MR field regarding types of scanners, data formats, protocols, and software/hardware versions, as well as the challenges and opportunities for unifying these datasets in a common interface, MRdataset.

This session covers the framework of the International Brain Lab (IBL) and the data architecture used for this project.

The number of patients with dementia is estimated to increase given the aging population. This will lead to a number of challenges in the future in terms of diagnosis and care for patients with dementia. To meet these needs such as early diagnsosis and development of prognostic biomarkers, large datasets, such as the federated datasets on dementia. The EAN Dementia and cognitive disorders scientific panel can play an important role as coordinator and connecting panel members who wish to participate in e.g. consortia.

This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

In this lesson, you will learn about how genetics can contribute to our understanding of psychiatric phenotypes.

The Allen Mouse Brain Atlas is a genome-wide, high-resolution atlas of gene expression throughout the adult mouse brain. This tutorial describes the basic search and navigation features of the Allen Mouse Brain Atlas.

The Allen Developing Mouse Brain Atlas is a detailed atlas of gene expression across mouse brain development. This tutorial describes the basic search and navigation features of the Allen Developing Mouse Brain Atlas.