This lightning talk describes an automated pipline for positron emission tomography (PET) data.
This session introduces the PET-to-BIDS (PET2BIDS) library, a toolkit designed to simplify the conversion and preparation of PET imaging datasets into BIDS-compliant formats. It supports multiple data types and formats (e.g., DICOM, ECAT7+, nifti, JSON), integrates seamlessly with Excel-based metadata, and provides automated routines for metadata updates, blood data conversion, and JSON synchronization. PET2BIDS improves human readability by mapping complex reconstruction names into standardized, descriptive labels and offers extensive documentation, examples, and video tutorials to make adoption easier for researchers.
This session introduces the PET-to-BIDS (PET2BIDS) library, a toolkit designed to simplify the conversion and preparation of PET imaging datasets into BIDS-compliant formats. It supports multiple data types and formats (e.g., DICOM, ECAT7+, nifti, JSON), integrates seamlessly with Excel-based metadata, and provides automated routines for metadata updates, blood data conversion, and JSON synchronization. PET2BIDS improves human readability by mapping complex reconstruction names into standardized, descriptive labels and offers extensive documentation, examples, and video tutorials to make adoption easier for researchers.
This session dives into practical PET tooling on BIDS data—showing how to run motion correction, register PET↔MRI, extract time–activity curves, and generate standardized PET-BIDS derivatives with clear QC reports. It introduces modular BIDS Apps (head-motion correction, TAC extraction), a full pipeline (PETPrep), and a PET/MRI defacer, with guidance on parameters, outputs, provenance, and why Dockerized containers are the reliable way to run them at scale.
This session introduces two PET quantification tools—bloodstream for processing arterial blood data and kinfitr for kinetic modeling and quantification—built to work with BIDS/BIDS-derivatives and containers. Bloodstream fuses autosampler and manual measurements (whole blood, plasma, parent fraction) using interpolation or fitted models (incl. hierarchical GAMs) to produce a clean arterial input function (AIF) and whole-blood curves with rich QC reports ready. TAC data (e.g., from PETPrep) and blood (e.g., from bloodstream) can be ingested using kinfitr to run reproducible, GUI-driven analyses: define combined ROIs, calculate weighting factors, estimate blood–tissue delay, choose and chain models (e.g., 2TCM → 1TCM with parameter inheritance), and export parameters/diagnostics. Both are available as Docker apps; workflows emphasize configuration files, reports, and standard outputs to support transparency and reuse.
This lecture covers positron emission tomography (PET) imaging and the Brain Imaging Data Structure (BIDS), and how they work together within the PET-BIDS standard to make neuroscience more open and FAIR.
This module covers many of the types of non-invasive neurotech and neuroimaging devices including electroencephalography (EEG), electromyography (EMG), electroneurography (ENG), magnetoencephalography (MEG), and more.
The goal of computational modeling in behavioral and psychological science is using mathematical models to characterize behavioral (or neural) data. Over the past decade, this practice has revolutionized social psychological science (and neuroscience) by allowing researchers to formalize theories as constrained mathematical models and test specific hypotheses to explain unobservable aspects of complex social cognitive processes and behaviors. This course is composed of 4 modules in the format of Jupyter Notebooks. This course comprises lecture-based, discussion-based, and lab-based instruction. At least one-third of class sessions will be hands-on. We will discuss relevant book chapters and journal articles, and work with simulated and real data using the Python programming language (no prior programming experience necessary) as we survey some selected areas of research at the intersection of computational modeling and social behavior. These selected topics will span a broad set of social psychological abilities including (1) learning from and for others, (2) learning about others, and (3) social influence on decision-making and mental states. Rhoads, S. A. & Gan, L. (2022). Computational models of human social behavior and neuroscience - An open educational course and Jupyter Book to advance computational training. Journal of Open Source Education, 5(47), 146. https://doi.org/10.21105/jose.00146
This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.
This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat.
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.
In this lesson, you will learn about how genetics can contribute to our understanding of psychiatric phenotypes.
The Allen Mouse Brain Atlas is a genome-wide, high-resolution atlas of gene expression throughout the adult mouse brain. This tutorial describes the basic search and navigation features of the Allen Mouse Brain Atlas.
The Allen Developing Mouse Brain Atlas is a detailed atlas of gene expression across mouse brain development. This tutorial describes the basic search and navigation features of the Allen Developing Mouse Brain Atlas.