In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.
Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface (GUI). Afterwards, the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.
This lecture provides an introductory overview of some of the most important concepts in software engineering.
This lecture provides an introduction to optogenetics, a biological technique to control the activity of neurons or other cell types with light.
This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.
This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.
This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.
This lesson is part 1 of 2 of a tutorial on statistical models for neural data.
What is the difference between attention and consciousness? This lecture describes the scientific meaning of consciousness, journeys on the search for neural correlates of visual consciousness, and explores the possibility of consciousness in other beings and even non-biological structures.
How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.
This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication.
This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.
In this lesson you will learn about ion channels and the movement of ions across the cell membrane, one of the key mechanisms underlying neuronal communication.
This lesson presents the typical setup, equipment, and solutions used in whole-cell recording of neurons.
This lesson provides an introductory overview to synaptic transmission and associated neurotransmitters.
Neurodata Without Borders (NWB) is a data standard for neurophysiology that provides neuroscientists with a common standard to share, archive, use, and build common analysis tools for neurophysiology data.
This lesson provides a brief introduction to the Neuroscience Information Exchange (NIX) Format data model, which allows storing fully annotated scientific datasets, i.e., data combined with rich metadata and their relations in a consistent, comprehensive format.
In this lecture, attendees will learn how Mutant Mouse Resource and Research Center (MMRRC) archives, cryopreserves, and distributes scientifically valuable genetically engineered mouse strains and mouse ES cell lines for the genetics and biomedical research community.
This lesson provides an overview of Neurodata Without Borders (NWB), an ecosystem for neurophysiology data standardization. The lecture also introduces some NWB-enabled tools.