This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.

This lecture provides an introduction to Plato’s concept of rationality and Aristotle’s concept of empiricism, and the enduring discussion between rationalism and empiricism to this day.

This lecture goes into further detail about the hard problem of developing a scientific discipline for subjective consciousness.

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

Maximize Your Research With Cloud Workspaces is a talk aimed at researchers who are looking for innovative ways to set up and execute their life science data analyses in a collaborative, extensible, open-source cloud environment. This panel discussion is brought to you by MetaCell and scientists from leading universities who share their experiences of advanced analysis and collaborative learning through the Cloud.

In this lesson, you will learn about data management within the Open Data Commons (ODC) framework, and in particular, how Spinal Cord Injury (SCI) data is stored, shared, and published. You will also hear about Frictionless Data, an open-source toolkit aimed at simplifying the data experience. 

This talk describes the NIH-funded SPARC Data Structure, and how this project navigates ontology development while keeping in mind the FAIR science principles. 

This talk goes over Neurobagel, an open-source platform developed for improved dataset sharing and searching. 

This video gives a brief introduction to the second session of talks from INCF's Neuroinformatics Assembly 2023. 

This talk enumerates the challenges regarding data accessibility and reusability inherent in the current scientific publication system, and discusses novel approaches to these challenges, such as the EBRAINS Live Papers platform. 

This brief video provides an introduction to the third session of INCF's Neuroinformatics Assembly 2023, focusing on how to streamling cross-platform data integration in a neuroscientific context. 

This talk describes the challenges to sustained operability and success of consortia, why many of these groups flounder after just a few years, and what steps can be taken to mitigate such outcomes. 

In this talk, you will learn about the standardization schema for data formats among two of the US BRAIN Initiative networks: the Cell Census Network (BICCN) and the Cell Atlas Network (BICAN). 

In this lesson, you will learn about the BRAIN Initiative Cell Atlas Network (BICAN) and how this project adopts a federated approach to data sharing. 

This talk discusses the BRAIN Initiative Cell Atlas Network (BICAN), taking a look specifically at how this network approaches the design, development, and maintenance of specimen and sequencing library portals.