The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
In this lesson, while learning about the need for increased large-scale collaborative science that is transparent in nature, users also are given a tutorial on using Synapse for facilitating reusable and reproducible research.
This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling.
Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.
This lesson provides an introduction the International Neuroinformatics Coordinating Facility (INCF), its mission towards FAIR neuroscience, and future directions.
This brief video provides an introduction to the third session of INCF's Neuroinformatics Assembly 2023, focusing on how to streamling cross-platform data integration in a neuroscientific context.
This final lesson of the course consists of the panel discussion for Streamlining Cross-Platform Data Integration session during the first day of INCF's Neuroinformatics Assembly 2023.
This lightning talk describes the heterogeneity of the MR field regarding types of scanners, data formats, protocols, and software/hardware versions, as well as the challenges and opportunities for unifying these datasets in a common interface, MRdataset.
This session covers the framework of the International Brain Lab (IBL) and the data architecture used for this project.
This lecture covers the ethical implications of the use of brain-computer interfaces, brain-machine interfaces, and deep brain stimulation to enhance brain functions and was part of the Neuro Day Workshop held by the NeuroSchool of Aix Marseille University.
This module covers many types of invasive neurotechnology devices/interfaces for the central and peripheral nervous systems. Invasive neurotech devices are crucial, as they often provide the greatest accuracy and long-term use applicability.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This is the second of three lectures around current challenges and opportunities facing neuroinformatic infrastructure for handling sensitive data.
In this lesson you will learn about current efforts towards integrating multimodal human brain data using the open source SCORE HED library schema.
This lecture aims to help researchers, students, and health care professionals understand the place for neuroinformatics in the patient journey using the exemplar of an epilepsy patient.
This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases.
This lecture continues from part one (previous lesson), highlighting our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases.
This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.