The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
This presentation by the OHBM OpenScienceSIG covers common scenarios where Git can be extremely valuable. The essentials covered include cloning a repository and keeping it up to date, how to create and use your own repository, and how to contribute to other projects via forking and pull requests.
DataLad is a versatile data management and data publication multi-tool. In this session, you can learn the basic concepts and commands for version control and reproducible data analysis. You’ll get to see, create, and install DataLad datasets of many shapes and sizes, master local version workflows and provenance-captured analysis-execution, and you will get ideas for your next data analysis project.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This is the second of three lectures around current challenges and opportunities facing neuroinformatic infrastructure for handling sensitive data.
In this lesson you will learn about current efforts towards integrating multimodal human brain data using the open source SCORE HED library schema.
This lecture aims to help researchers, students, and health care professionals understand the place for neuroinformatics in the patient journey using the exemplar of an epilepsy patient.
This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases.
This lecture continues from part one (previous lesson), highlighting our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases.
This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.
This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.
This lecture provides an introduction to entropy in general, and multi-scale entropy (MSE) in particular, highlighting the potential clinical applications of the latter.
This lecture provides an general introduction to epilepsy, as well as why and how TVB can prove useful in building and testing epileptic models.
The INS Emerging Issues Task Force held a virtual panel discussion on the evolving role and increased adoption of digital applications to deliver mental health care. It was held as a session at the annual conference of the Italian Society for Neuroethics.
This lecture covers the rationale for developing the DAQCORD, a framework for the design, documentation, and reporting of data curation methods in order to advance the scientific rigour, reproducibility, and analysis of data.
This lecture focuses on ontologies for clinical neurosciences.
This talks presents an overview of the potential for data federation in stroke research.