The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies.
This lesson corresponds to slides 46-78 of the PDF below.
This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.
This lesson corresponds to slides 1-50 of the PowerPoint below.
This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling.
This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves.
In this lesson, users learn how to use MATLAB to build an adaptive exponential integrate and fire (AdEx) neuron model.
In this lesson, users learn about the practical differences between MATLAB scripts and functions, as well as how to embed their neuronal simulation into a callable function.
This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F).
This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.
This brief talk goes into work being done at The Alan Turing Institute to solve real-world challenges and democratize computer vision methods to support interdisciplinary and international researchers.
This lesson aims to define computational neuroscience in general terms, while providing specific examples of highly successful computational neuroscience projects.
This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models.
In this lesson you will learn how machine learners and neuroscientists construct abstract computational models based on various neurophysiological signalling properties.
In this lesson, you will learn about some typical neuronal models employed by machine learners and computational neuroscientists, meant to imitate the biophysical properties of real neurons.
This lesson contains practical exercises which accompanies the first few lessons of the Neuroscience for Machine Learners (Neuro4ML) course.
In this lesson, you will learn about how machine learners and computational neuroscientists design and build models of neuronal synapses.
This lesson introduces some practical exercises which accompany the Synapses and Networks portion of this Neuroscience for Machine Learners course.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
In this lesson, you will learn more about some of the issues inherent in modeling neural spikes, approaches to ameliorate these problems, and the pros and cons of these approaches.
In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way.