This lecture provides an introduction to optogenetics, a biological technique to control the activity of neurons or other cell types with light.

This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

The INS Emerging Issues Task Force held a virtual panel discussion on the evolving role and increased adoption of digital applications to deliver mental health care. It was held as a session at the annual conference of the Italian Society for Neuroethics.

This lecture covers visualizing extracellular neurotransmitter dynamics

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

This lecture consists of the second half of the introduction to signal transduction, here focusing on cell receptors and signalling cascades.

In this lesson, you will learn about GABAergic interneurons and local inhibition on the circuit level.

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

In this lesson, you will learn about how machine learners and computational neuroscientists design and build models of neuronal synapses. 

How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.

This lesson goes into the mechanisms behind changes in synaptic function created by learning.

This lecture provides an introduction to the study of eye-tracking in humans. 

From the retina to the superior colliculus, the lateral geniculate nucleus into primary visual cortex and beyond, this lecture gives a tour of the mammalian visual system highlighting the Nobel-prize winning discoveries of Hubel & Wiesel.

From Universal Turing Machines to McCulloch-Pitts and Hopfield associative memory networks, this lecture explains what is meant by computation.