This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
This lesson provides a brief introduction to the Computational Modeling of Neuronal Plasticity.
In this lesson, you will be introducted to a type of neuronal model known as the leaky integrate-and-fire (LIF) model.
This lesson goes over various potential inputs to neuronal synapses, loci of neural communication.
This lesson describes the how and why behind implementing integration time steps as part of a neuronal model.
In this lesson, you will learn about neural spike trains which can be characterized as having a Poisson distribution.
This lesson covers spike-rate adaptation, the process by which a neuron's firing pattern decays to a low, steady-state frequency during the sustained encoding of a stimulus.
This lesson provides a brief explanation of how to implement a neuron's refractory period in a computational model.
In this lesson, you will learn a computational description of the process which tunes neuronal connectivity strength, spike-timing-dependent plasticity (STDP).
This lesson reviews theoretical and mathematical descriptions of correlated spike trains.
This lesson investigates the effect of correlated spike trains on spike-timing dependent plasticity (STDP).
This lesson goes over synaptic normalisation, the homeostatic process by which groups of weighted inputs scale up or down their biases.
In this lesson, you will learn about the intrinsic plasticity of single neurons.
This lesson covers short-term facilitation, a process whereby a neuron's synaptic transmission is enhanced for a short (sub-second) period.
This lesson describes short-term depression, a reduction of synaptic information transfer between neurons.
This lesson briefly wraps up the course on Computational Modeling of Neuronal Plasticity.
Learn how to create a standard extracellular electrophysiology dataset in NWB using Python.
Learn how to create a standard calcium imaging dataset in NWB using Python.
In this tutorial, you will learn how to create a standard intracellular electrophysiology dataset in NWB using Python.
In this tutorial, you will learn how to use the icephys-metadata extension to enter meta-data detailing your experimental paradigm.