Ethical conduct of science, good governance of data, and accelerated translation to the clinic are key to high-calibre open neuroscience.  Everyday practitioners of science must be sensitized to a range of ethical considerations in their research, some having especially to do with open data-sharing. The lessons included in this course introduce a number of these topics and end with concrete guidance for participant consent and de-identification of data.

This course contains videos, lectures, and hands-on tutorials as part of INCF's Neuroinformatics Assembly 2023 workshop on developing robust and reproducible research workflows to foster greater collaborative efforts in neuroscience.

In this course we present the TVB-EBRAINS integrated workflows that have been developed in the Human Brain Project in the third funding phase (“SGA2”) in the Co-Design Project 8 “The Virtual Brain”. 

This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression). 

Bayesian inference (using prior knowledge to generate more accurate predictions about future events or outcomes) has become increasingly applied to the fields of neuroscience and neuroinformatics. In this course, participants are taught how Bayesian statistics may be used to build cognitive models of processes like learning or perception. This course also offers theoretical and practical instruction on dynamic causal modeling as applied to fMRI and EEG data.

This course is intended to introduce researchers to the Open Science Framework (OSF). OSF is a free, open source web application built by the Center for Open Science, a non-profit dedicated to improving the alignment between scientific values and scientific practices. OSF is part collaboration tool, part version control software, and part data archive.

Difficulties experienced in understanding machine learning techniques often stem from lack of clarity concerning more basic statistical models and fundamental considerations, including the various regression models that can all be subsumed under the General Linear Model.

Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.

EEGLAB is an interactive MATLAB toolbox for processing continuous and event-related EEG, MEG, and other electrophysiological data. In this course, you will learn about features incorporated into EEGLAB, including independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data. EEGLAB runs under Linux, Unix, Windows, and Mac OS X.

Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.

Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools.

This course contains sessions from the first day of INCF's Neuroinformatics Assembly 2022.

Sessions from the INCF Neuroinformatics Assembly 2022 day 1. 

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Over the last three decades, neuroimaging research has seen large strides in the scale, diversity, and complexity of studies, the open availability of data and methodological resources, the quality of instrumentation and multimodal studies, and the number of researchers and consortia. The awareness of rigor and reproducibility has increased with the advent of funding mandates, and with the work done by national and international brain initiatives.

Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.

In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.

This course provides several visual walkthroughs documenting how to execute various processes in brainlife.io, an open-source, free and secure reproducible neuroscience analysis platform. The platform allows to analyze Magnetic Resonance Imaging (MRI), electroencephalography (EEG) and magnetoencephalography (MEG) data. Data can either be uploaded from local computers or imported from public archives such as OpenNeuro.org.

Given the extreme interconnectedness of the human brain, studying any one cerebral area in isolation may lead to spurious results or incomplete, if not problematic, interpretations. This course introduces participants to the various spatial scales of neuroscience and the fundamentals of whole-brain modelling, used to generate a more thorough picture of brain activity.

As technological improvements continue to facilitate innovations in the mental health space, researchers and clinicians are faced with novel opportunities and challenges regarding study design, diagnoses, treatments, and follow-up care. This course includes a lecture outlining these new developments, as well as a workshop which introduces users to Synapse, an open-source platform for collaborative data analysis. 

This course contains sessions from the second day of INCF's Neuroinformatics Assembly 2022.