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The neuroinformatics of neuroanatomy

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Category
Level
Beginner

This workshop focus on what is required of those working in neuroanatomy to make their data suitable for and compliant with neuroinformatics systems.

Workshop at Neuroinformatics 2014 in Leiden, The Netherlands

Workshop abstract

Neuroanatomy provides one of the unifying frameworks for neuroscience and thus it is not surprising that it provides the basis for many neuroinformatics tools and approaches.  Regardless of whether one is working at the subcellular, cellular or gross anatomical level or whether one is modeling circuitry, molecular pathways or function, at some point, this work will include an anatomical reference. The brain is perhaps unique in the number of nomenclatures and strategies for parcellating its anatomy. Yet this diversity creates a headache for current information systems, which must attempt to reconcile the different reference systems developed.  This workshop will focus on what is required of those working in neuroanatomy to make their data suitable for and compliant with neuroinformatics systems, so that it can be compared computationally to other work and reused by others, including those who are working in genomics, proteomics, physiology, and other forms of behavior.  Thus, the aim is to focus less on exactly how one parcellates a brain and more on how one models this parcellation to make the information usable. We will hear from researchers working on informatics systems that include an atlasing component about their approaches and best practices.

Importance of correct annotation and assignment of location
The digital renaissance of human neuroanatomy
Essential features of digital brain models for neuroinformatics
Neuroinformatics and digital atlases of the Allen Institute for Brain Science
Lessons of this Course
1
Duration:
5:36

The chair of the workshop is giving an introduction and a motivating argument.

2
Duration:
22:04

This lecture highlights the importance of correct annotation and assignment of location, and updated atlas resources to avoid errors in navigation and data interpretation.

3
Duration:
25:27

We are at the exciting technological stage where it has become feasible to represent the anatomy of an entire human brain at the cellular level. In this presentation, the speaker explains that neuroanatomy in the XXI Century has become an effort towards the virtualization and standardization of brain tissue.

4
Duration:
22:26

This lecture covers essential features of digital brain models for neuroinformatics.

5
Duration:
23:41

This presentation covers the neuroinformatics tools and techniques used and their relationship to neuroanatomy for the Allen atlases of the mouse, developing mouse, and mouse connectional atlas.