This talks discusses data sharing in the context of dementia. It explains why data sharing in dementia is important, how data is usually shared in the field and illustrates two examples: the Netherlands Consortium Dementia cohorts and the European Platform for Neurodegenerative Diseases.

The Medical Informatics Platform (MIP) Dementia had been installed in several memory clinics across Europe allowing them to federate their real-world databases. Research open access databases had also been integrated such as ADNI (Alzheimer’s Dementia Neuroimaging Initiative), reaching a cumulative case load of more than 5,000 patients (major cognitive disorder due to Alzheimer’s disease, other major cognitive disorder, minor cognitive disorder, controls). The statistic and machine learning tools implemented in the MIP allowed researchers to conduct easily federated analyses among Italian memory clinics (Redolfi et al. 2020) and also across borders between the French (Lille), the Swiss (Lausanne) and the Italian (Brescia) datasets.

The number of patients with dementia is estimated to increase given the aging population. This will lead to a number of challenges in the future in terms of diagnosis and care for patients with dementia. To meet these needs such as early diagnsosis and development of prognostic biomarkers, large datasets, such as the federated datasets on dementia. The EAN Dementia and cognitive disorders scientific panel can play an important role as coordinator and connecting panel members who wish to participate in e.g. consortia.

This lecture presents the Medical Informatic Platform's data federation for Traumatic Brain Injury.

This lecture gives insights into the Medical Informatics Platform's current and future data privacy model.

This lecture explains the concept of federated analysis in the context of medical data, associated challenges. The lecture also presents an example of hospital federations via the Medical Informatics Platform.

This talk discusses what are usually considered successful outcomes of scientific research consortia, and how those outcomes can be translated into lasting impacts. 

In this lesson, you will learn about the BRAIN Initiative Cell Atlas Network (BICAN) and how this project adopts a federated approach to data sharing. 

This talks presents an overview of the potential for data federation in stroke research.

This lecture explains the need for data federation in medicine and how it can be achieved.

This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Maximize Your Research With Cloud Workspaces is a talk aimed at researchers who are looking for innovative ways to set up and execute their life science data analyses in a collaborative, extensible, open-source cloud environment. This panel discussion is brought to you by MetaCell and scientists from leading universities who share their experiences of advanced analysis and collaborative learning through the Cloud.

This talk enumerates the challenges regarding data accessibility and reusability inherent in the current scientific publication system, and discusses novel approaches to these challenges, such as the EBRAINS Live Papers platform. 

In this lesson, you will learn about how team science unfolds in practice, as well as what are the standards and best practices used by teams, and how well these best practices function and support scientific output. 

In this lesson, you will learn about approaches to make the field of neuroscience more open and fair, particularly regarding the integration of equality, diversity, and inclusion (EDI) as guiding principles for team collaboration. 

This lesson discusses the topic of credit and contribution in open and FAIR neuroscience, looking through the respective lenses of systems, teams, and people. 

In this talk, you will hear about the challenges and costs of being FAIR in the many scientific fields, as well as opportunities to transform the ecology of the academic crediting system.