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This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies. 

 

This lesson corresponds to slides 46-78 of the PDF below. 

Difficulty level: Beginner
Duration: 1:12:25
Speaker: : Joanna Yu

This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.

 

This lesson corresponds to slides 1-50 of the PowerPoint below. 

Difficulty level: Beginner
Duration: 1:24:30
Speaker: : Dan Felsky

This lecture covers the needs and challenges involved in creating a FAIR ecosystem for neuroimaging research.

Difficulty level: Beginner
Duration: 12:26
Speaker: : Camille Maumet

This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.

Difficulty level: Beginner
Duration: 15:14

This lecture focuses on the structured validation process within computational neuroscience, including the tools, services, and methods involved in simulation and analysis.

Difficulty level: Beginner
Duration: 14:19
Speaker: : Michael Denker
Course:

This session provides users with an introduction to tools and resources that facilitate the implementation of FAIR in their research.

 

 

Difficulty level: Beginner
Duration: 38:36

This is the third and final lecture of this course on neuroinformatics infrastructure for handling sensitive data. 

Difficulty level: Beginner
Duration: 1:11:22
Speaker: : Michael Schirner

In this lecture, you will learn about virtual research environments (VREs) and their technical limitations, (i.e., a computing platform and the software stack behind it) and the security measures which should be considered during implementation. 

Difficulty level: Beginner
Duration: 1:06:50
Speaker: : Marc Sacks

This lecture discusses the challenges of protecting hospital data.

Difficulty level: Intermediate
Duration: 12:48

This lecture discusses differential privacy and synthetic data in the context of medical data sharing in clinical neurosciences.

Difficulty level: Intermediate
Duration: 20:26

This talk presents state-of-the-art methods for ensuring data privacy with a particular focus on medical data sharing across multiple organizations.

Difficulty level: Intermediate
Duration: 22:49

In this talk the speakers will give a brief introduction of the Fenix Infrastructure and Service Offering, before focusing on Data Safety. The speaker will take the participants through the ETHZ-CSCS offering for EBRAINS and all the HBP Communities highlighting the Infrastructure role in a service implementation in respect of Security. Particular attention will be on showing what tools ETHZ-CSCS provides to a Portal/Service provider such as EBRAINS, MIP/HIP, TVB, NRP amongst others. Finally there will be given a quick glimpse into the future and the role that “multi-tenancy” will play.

Difficulty level: Intermediate
Duration: 20:05

This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.

Difficulty level: Beginner
Duration: 37:47

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

Difficulty level: Intermediate
Duration: 1:28:16
Speaker: : Dan Felsky

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

Difficulty level: Intermediate
Duration:
Speaker: : Dan Felsky

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

Difficulty level: Intermediate
Duration: 1:29:08

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

Difficulty level: Intermediate
Duration: 1:19:17
Speaker: : Sonny Chen

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Difficulty level: Intermediate
Duration: 1:15:14
Speaker: : Keon Arbabi