The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

This lecture covers the IBI Data Standards and Sharing Working Group, including its history, aims, and projects.

This session covers the framework of the International Brain Lab (IBL) and the data architecture used for this project.

This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.

This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models. 

Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation. 

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

This lesson covers the ionic basis of the action potential, including the Hodgkin-Huxley model. 

This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication. 

In this lesson you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model. 

This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.

This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level. 

This lesson covers the spatiotemporal dynamics of the membrane potential.

In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.

This lesson discusses voltage-gating kinetics of sodium and potassium channels.

In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

This lesson delves into the specifics of how action potentials propagate through individual neurons.

In this lesson, you will learn about neurotransmitter release in the presynaptic specialization.