This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies. 

This lesson corresponds to slides 46-78 of the PDF below. 

This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.

This lesson corresponds to slides 1-50 of the PowerPoint below. 

This lecture covers the needs and challenges involved in creating a FAIR ecosystem for neuroimaging research.

This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.

This lecture focuses on the structured validation process within computational neuroscience, including the tools, services, and methods involved in simulation and analysis.

This session provides users with an introduction to tools and resources that facilitate the implementation of FAIR in their research.

This talks discusses data sharing in the context of dementia. It explains why data sharing in dementia is important, how data is usually shared in the field and illustrates two examples: the Netherlands Consortium Dementia cohorts and the European Platform for Neurodegenerative Diseases.

The Medical Informatics Platform (MIP) Dementia had been installed in several memory clinics across Europe allowing them to federate their real-world databases. Research open access databases had also been integrated such as ADNI (Alzheimer’s Dementia Neuroimaging Initiative), reaching a cumulative case load of more than 5,000 patients (major cognitive disorder due to Alzheimer’s disease, other major cognitive disorder, minor cognitive disorder, controls). The statistic and machine learning tools implemented in the MIP allowed researchers to conduct easily federated analyses among Italian memory clinics (Redolfi et al. 2020) and also across borders between the French (Lille), the Swiss (Lausanne) and the Italian (Brescia) datasets.

The number of patients with dementia is estimated to increase given the aging population. This will lead to a number of challenges in the future in terms of diagnosis and care for patients with dementia. To meet these needs such as early diagnsosis and development of prognostic biomarkers, large datasets, such as the federated datasets on dementia. The EAN Dementia and cognitive disorders scientific panel can play an important role as coordinator and connecting panel members who wish to participate in e.g. consortia.

This lesson provides an overview of the current status in the field of neuroscientific ontologies, presenting examples of data organization and standards, particularly from neuroimaging and electrophysiology. 

Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation. 

This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system. 

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication. 

This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.

In this lesson you will learn about ion channels and the movement of ions across the cell membrane, one of the key mechanisms underlying neuronal communication. 

This lesson presents the typical setup, equipment, and solutions used in whole-cell recording of neurons. 

This lesson provides an introductory overview to synaptic transmission and associated neurotransmitters. 

This lecture covers NeuronUnit, a library that builds upon SciUnit and integrates with several existing neuroinformatics resources to support validating single-neuron models using data gathered by neurophysiologists.

This lesson provides an introduction to the NeuroElectro project, which aims to organize information on cellular neurophysiology.