The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies. 

This lesson corresponds to slides 46-78 of the PDF below. 

This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.

This lesson corresponds to slides 1-50 of the PowerPoint below. 

This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling. 

In this talk the speakers will give a brief introduction of the Fenix Infrastructure and Service Offering, before focusing on Data Safety. The speaker will take the participants through the ETHZ-CSCS offering for EBRAINS and all the HBP Communities highlighting the Infrastructure role in a service implementation in respect of Security. Particular attention will be on showing what tools ETHZ-CSCS provides to a Portal/Service provider such as EBRAINS, MIP/HIP, TVB, NRP amongst others. Finally there will be given a quick glimpse into the future and the role that “multi-tenancy” will play.

This lesson provides an overview of the current status in the field of neuroscientific ontologies, presenting examples of data organization and standards, particularly from neuroimaging and electrophysiology. 

Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation. 

This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system. 

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication. 

This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.

In this lesson you will learn about ion channels and the movement of ions across the cell membrane, one of the key mechanisms underlying neuronal communication. 

This lesson presents the typical setup, equipment, and solutions used in whole-cell recording of neurons. 

This lesson provides an introductory overview to synaptic transmission and associated neurotransmitters. 

This lecture covers NeuronUnit, a library that builds upon SciUnit and integrates with several existing neuroinformatics resources to support validating single-neuron models using data gathered by neurophysiologists.

This lesson provides an introduction to the NeuroElectro project, which aims to organize information on cellular neurophysiology.

This lesson covers simultaneously recorded neurons in non-human primates coordinate their spiking activity in a sequential manner that mirrors the dominant wave propagation directions of the local field potentials.

This talk covers statistical analysis of spike train data, the modeling approach GLM, and the problem of assessing neural synchrony.

This talk covers statistical methods for characterizing neural population responses and extracting structure from high-dimensional neural data.

This presentation discusses research aimed at understanding the activity of single neurons and populations of neurons in the visual system.