This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies.
This lesson corresponds to slides 46-78 of the PDF below.
This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.
This lesson corresponds to slides 1-50 of the PowerPoint below.
This lecture covers the needs and challenges involved in creating a FAIR ecosystem for neuroimaging research.
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
This lecture focuses on the structured validation process within computational neuroscience, including the tools, services, and methods involved in simulation and analysis.
This session provides users with an introduction to tools and resources that facilitate the implementation of FAIR in their research.
This lecture covers visualizing extracellular neurotransmitter dynamics
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?
This lecture consists of the second half of the introduction to signal transduction, here focusing on cell receptors and signalling cascades.
In this lesson, you will learn about GABAergic interneurons and local inhibition on the circuit level.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
This lesson explains the fundamental principles of neuronal communication, such as neuronal spiking, membrane potentials, and cellular excitability, and how these electrophysiological features of the brain may be modelled and simulated digitally.
This is an in-depth guide on EEG signals and their interaction within brain microcircuits. Participants are also shown techniques and software for simulating, analyzing, and visualizing these signals.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.
This lecture covers the emergence of cognitive science after the Second World War as an interdisciplinary field for studying the mind, with influences from anthropology, cybernetics, and artificial intelligence.
In this lesson, you will learn about the connectome, the collective system of neural pathways in an organism, with a closer look at the neurons, synapses, and connections of particular species.
This lesson delves into the human nervous system and the immense cellular, connectomic, and functional sophistication therein.