The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies. 

This lesson corresponds to slides 46-78 of the PDF below. 

This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.

This lesson corresponds to slides 1-50 of the PowerPoint below. 

This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling. 

This lecture covers computational principles that growth cones employ to detect and respond to environmental chemotactic gradients, focusing particularly on growth-cone shape dynamics.

In this lecture you will learn that in developing mouse somatosensory cortex, endogenous Btbd3 translocate to the cell nucleus in response to neuronal activity and oriente primary dendrites toward active axons in the barrel hollow.

In this presentation, the speaker describes some of their recent efforts to characterize the transcriptome of the developing human brain, and and introduction to the BrainSpan project.

How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.