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Computational principles of axon guidance

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Difficulty level
Intermediate
Speaker
Type
Duration
26:12

This lecture covers computational principles that growth cones employ to detect and respond to environmental chemotactic gradients, focusing particularly on growth cone shape dynamics.

Topics covered in this lesson
  • Recent experimental and theoretical work attempting to uncover the computational principles that growth cones employ to detect and respond to environmental chemotactic gradients, focusing particularly on growth cone shape dynamics.
  • How just a few shape primitives capture most of the shape variance of growth cones, and that periodic oscillations play a critical role in their shape dynamic