The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies.
This lesson corresponds to slides 46-78 of the PDF below.
This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.
This lesson corresponds to slides 1-50 of the PowerPoint below.
This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling.
This talk describes the NIH-funded SPARC Data Structure, and how this project navigates ontology development while keeping in mind the FAIR science principles.
This lesson provides an overview of the current status in the field of neuroscientific ontologies, presenting examples of data organization and standards, particularly from neuroimaging and electrophysiology.
This lesson continues from part one of the lecture Ontologies, Databases, and Standards, diving deeper into a description of ontologies and knowledg graphs.
This lecture covers structured data, databases, federating neuroscience-relevant databases, and ontologies.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
This lecture focuses on ontologies for clinical neurosciences.
This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.
This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models.
Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation.
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time.
Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks.
This lesson covers the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication.
In this lesson you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.