This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

This lesson provides an overview of the database of Genotypes and Phenotypes (dbGaP), which was developed to archive and distribute the data and results from studies that have investigated the interaction of genotype and phenotype in humans.

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

This lesson provides a brief introduction to the Computational Modeling of Neuronal Plasticity.

In this lesson, you will be introducted to a type of neuronal model known as the leaky integrate-and-fire (LIF) model.

This lesson goes over various potential inputs to neuronal synapses, loci of neural communication.

This lesson describes the how and why behind implementing integration time steps as part of a neuronal model.

In this lesson, you will learn about neural spike trains which can be characterized as having a Poisson distribution.

This lesson covers spike-rate adaptation, the process by which a neuron's firing pattern decays to a low, steady-state frequency during the sustained encoding of a stimulus.

This lesson provides a brief explanation of how to implement a neuron's refractory period in a computational model.

In this lesson, you will learn a computational description of the process which tunes neuronal connectivity strength, spike-timing-dependent plasticity (STDP).

This lesson reviews theoretical and mathematical descriptions of correlated spike trains.

This lesson investigates the effect of correlated spike trains on spike-timing dependent plasticity (STDP).

This lesson goes over synaptic normalisation, the homeostatic process by which groups of weighted inputs scale up or down their biases.

In this lesson, you will learn about the intrinsic plasticity of single neurons.

This lesson covers short-term facilitation, a process whereby a neuron's synaptic transmission is enhanced for a short (sub-second) period.

This lesson describes short-term depression, a reduction of synaptic information transfer between neurons.

This lesson briefly wraps up the course on Computational Modeling of Neuronal Plasticity.

This lesson provides an introduction the International Neuroinformatics Coordinating Facility (INCF), its mission towards FAIR neuroscience, and future directions. 

This talk describes the NIH-funded SPARC Data Structure, and how this project navigates ontology development while keeping in mind the FAIR science principles.