The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity.
This lesson describes a definitional framework for fairness and health equity in the age of the algorithm. While acknowledging the impressive capability of machine learning to positively affect health equity, this talk outlines potential (and actual) pitfalls which come with such powerful tools, ultimately making the case for collaborative, interdisciplinary, and transparent science as a way to operationalize fairness in health equity.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
In this lesson, while learning about the need for increased large-scale collaborative science that is transparent in nature, users also are given a tutorial on using Synapse for facilitating reusable and reproducible research.
This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies.
This lesson corresponds to slides 46-78 of the PDF below.
This lesson describes not only the need for precision medicine, but also the current state of the methods, pharmacogenetic approaches, utility and implementation of such care today.
This lesson corresponds to slides 1-50 of the PowerPoint below.
This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling.
This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
This lesson gives an introductory presentation on how data science can help with scientific reproducibility.
This lesson discusses FAIR principles and methods currently in development for assessing FAIRness.
The lecture provides an overview of the core skills and practical solutions required to practice reproducible research.
This lecture covers the biomedical researcher's perspective on FAIR data sharing and the importance of finding better ways to manage large datasets.
This lecture covers multiple aspects of FAIR neuroscience data: what makes it unique, the challenges to making it FAIR, the importance of overcoming these challenges, and how data governance comes into play.
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
This lecture covers the processes, benefits, and challenges involved in designing, collecting, and sharing FAIR neuroscience datasets.
This lecture covers the benefits and difficulties involved when re-using open datasets, and how metadata is important to the process.
This lecture provides guidance on the ethical considerations the clinical neuroimaging community faces when applying the FAIR principles to their research.
This lecture will provide an overview of Addgene, a tool that embraces the FAIR principles developed by members of the INCF Community. This will include an overview of Addgene, their mission, and available resources.