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This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves. 

Difficulty level: Intermediate
Duration: 8:21
Speaker: : Mike X. Cohen

In this lesson, users learn how to use MATLAB to build an adaptive exponential integrate and fire (AdEx) neuron model. 

Difficulty level: Intermediate
Duration: 22:01
Speaker: : Mike X. Cohen

In this lesson, users learn about the practical differences between MATLAB scripts and functions, as well as how to embed their neuronal simulation into a callable function.  

Difficulty level: Intermediate
Duration: 11:20
Speaker: : Mike X. Cohen

This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F). 

Difficulty level: Intermediate
Duration: 20:39
Speaker: : Mike X. Cohen

This lecture covers the linking neuronal activity to behavior using AI-based online detection. 

Difficulty level: Beginner
Duration: 30:39

This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

Difficulty level: Beginner
Duration: 1:16:04

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

Difficulty level: Intermediate
Duration: 1:19:17
Speaker: : Sonny Chen

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Difficulty level: Intermediate
Duration: 1:15:14
Speaker: : Keon Arbabi

This is a tutorial on how to simulate neuronal spiking in brain microcircuit models, as well as how to analyze, plot, and visualize the corresponding data. 

Difficulty level: Intermediate
Duration: 1:39:50
Speaker: : Frank Mazza

This tutorial introduces pipelines and methods to compute brain connectomes from fMRI data. With corresponding code and repositories, participants can follow along and learn how to programmatically preprocess, curate, and analyze functional and structural brain data to produce connectivity matrices. 

Difficulty level: Intermediate
Duration: 1:39:04
Course:

Maximize Your Research With Cloud Workspaces is a talk aimed at researchers who are looking for innovative ways to set up and execute their life science data analyses in a collaborative, extensible, open-source cloud environment. This panel discussion is brought to you by MetaCell and scientists from leading universities who share their experiences of advanced analysis and collaborative learning through the Cloud.

 

Difficulty level: Beginner
Duration: 55:43

This lecture goes into detailed description of how to process workflows in the virtual research environment (VRE), including approaches for standardization, metadata, containerization, and constructing and maintaining scientific pipelines. 

Difficulty level: Intermediate
Duration: 1:03:55
Speaker: : Patrik Bey

This lesson provides an overview of how to conceptualize, design, implement, and maintain neuroscientific pipelines in via the cloud-based computational reproducibility platform Code Ocean. 

Difficulty level: Beginner
Duration: 17:01
Speaker: : David Feng

This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.

Difficulty level: Beginner
Duration: 17:37
Speaker: : Dimitri Yatsenko

This talk describes approaches to maintaining integrated workflows and data management schema, taking advantage of the many open source, collaborative platforms already existing.

Difficulty level: Beginner
Duration: 15:15
Speaker: : Erik C. Johnson

This lesson is the first of three hands-on tutorials as part of the workshop Research Workflows for Collaborative Neuroscience. This tutorial goes over how to visualize data with Scanpy, a scalable toolkit for analyzing single-cell gene expression. 

Difficulty level: Intermediate
Duration: 25:26

This hands-on tutorial walks you through DataJoint platform, highlighting features and schema which can be used to build robost neuroscientific pipelines. 

Difficulty level: Beginner
Duration: 26:06
Speaker: : Milagros Marin