This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

 In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way. 

In this lesson, you will learn how to train spiking neural networks (SNNs) with a surrogate gradient method. 

In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

This lecture will provide an overview of neuroimaging techniques and their clinical applications.

This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.

This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases. 

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.

In this lesson, you will learn about how genetics can contribute to our understanding of psychiatric phenotypes.

This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.

This lesson gives an introduction to simple spiking neuron models.

This lesson provides an introduction to simple spiking neuron models.