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Fundamental Methods for Single-Cell Transcriptome Analysis

Krembil Centre for Neuroinformatics

This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression). 

 

The Future of Medical Data Sharing in Clinical Neurosciences

EBRAINS

This workshop hosted by HBP, EBRAINS, and the European Academy of Neurology (EAN) aimed to identify and openly discuss all issues and challenges associated with data sharing in Europe: from ethics to data safety and privacy including those specific to data federation such as the development and validation of federated algorithms. 

 

 

Module 1: Spikes

Mike X. Cohen

The goal of this module is to work with action potential data taken from a publicly available database. You will learn about spike counts, orientation tuning, and spatial maps. The MATLAB code introduces data types, for-loops and vectorizations, indexing, and data visualization.

 

The Virtual Brain Education Pack (TVB EduPack)

The Virtual Brain

The Virtual Brain EduPack provides didactic use cases for The Virtual Brain (TVB). Typically a use case consists of a jupyter notebook and a didactic video. EduPack use cases help the user to reproduce TVB-based publications or to get started quickly with TVB.

 

Whole-Brain Modelling

Krembil Centre for Neuroinformatics

Given the extreme interconnectedness of the human brain, studying any one cerebral area in isolation may lead to spurious results or incomplete, if not problematic, interpretations. This course introduces participants to the various spatial scales of neuroscience and the fundamentals of whole-brain modelling, used to generate a more thorough picture of brain activity.

 

Statistical Software

These courses give introductions and overviews of some of the major statistics software packages currently used in neuroscience research.

 

Fundamental Methods for Single-Cell Transcriptome Analysis

Krembil Centre for Neuroinformatics

This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression). 

 

Introduction to Neurodata Without Borders (NWB) for Python Users II

NWB Core Development Team

The Neurodata Without Borders: Neurophysiology project (NWB:N, https://www.nwb.org/) is an effort to standardize the description and storage of neurophysiology data and metadata. NWB enables data sharing and reuse and reduces the energy barrier to applying data analytics both within and across labs. Several laboratories, including the Allen Institute for Brain Science, have wholeheartedly adopted NWB.

 

The International Brain Initiative (IBI)

INCF

The International Brain Initiative (IBI) is a consortium of the world’s major large-scale brain initiatives and other organizations with a vested interest in catalyzing and advancing neuroscience research through international collaboration and knowledge sharing. This session will introduce the IBI and the current efforts of the Data Standards and Sharing Working Group with a view to gain input from a wider neuroscience and neuroinformatics community. 

 

Fundamental Methods for Genomic Analysis

Krembil Centre for Neuroinformatics

This course includes both lectures and tutorials around the management and analysis of genomic data in clinical research and care. Participants are led through the basics of genome-wide association studies (GWAS), genotypes, and polygenic risk scores, as well as novel concepts and tools for more sophisticated consideration of population stratification in GWAS.

 

Fundamental Methods for Genomic Analysis

Krembil Centre for Neuroinformatics

This course includes both lectures and tutorials around the management and analysis of genomic data in clinical research and care. Participants are led through the basics of genome-wide association studies (GWAS), genotypes, and polygenic risk scores, as well as novel concepts and tools for more sophisticated consideration of population stratification in GWAS.

 
INCF TrainingSpace

Computational Modeling of Neuronal Plasticity

Florence I. Kleberg and Jochen Triesch

In this course, you will learn how computational neuroscientists use mathematical models and computer simulations to study different plasticity phenomena in the brain. During the course, you will program your own neuron model, a so-called leaky-integrate-and-fire (LIF) neuron model, and simulate it with a computer. You will also learn how to add various neuronal properties and plasticity mechanisms to the model and study how they operate.

 

Bayesian Models of Learning and Integration of Neuroimaging Data

Krembil Centre for Neuroinformatics

Bayesian inference (using prior knowledge to generate more accurate predictions about future events or outcomes) has become increasingly applied to the fields of neuroscience and neuroinformatics. In this course, participants are taught how Bayesian statistics may be used to build cognitive models of processes like learning or perception. This course also offers theoretical and practical instruction on dynamic causal modeling as applied to fMRI and EEG data.

 

Module 4: fMRI

Mike X. Cohen

This module covers fMRI data, including creating and interpreting flatmaps, exploring variability and average responses, and visual eccenticity. You will learn about processing BOLD signals, trial-averaging, and t-tests. The MATLAB code introduces data animations, multicolor visualizations, and linear indexing.

 

The Virtual Brain Education Pack (TVB EduPack)

The Virtual Brain

The Virtual Brain EduPack provides didactic use cases for The Virtual Brain (TVB). Typically a use case consists of a jupyter notebook and a didactic video. EduPack use cases help the user to reproduce TVB-based publications or to get started quickly with TVB.

 
INCF TrainingSpace

Data Science in MATLAB®

The MathWorks, Inc

This course consists of a series of lessons and tutorials aimed at providing an introductory overview of data science implementation in MATLAB®, a widely used, numeric and computing platform which works with many types of data and file formats. In this course, you will learn the basic concepts behind data science in general, as well as how to apply those concepts within the MATLAB framework in particular.

 
INCF TrainingSpace

Session 3: Streamlining Cross-Platform Data Integration

INCF

This course corresponds to the third session of talks given at INCF's Neuroinformatics Assembly 2023. In this session, the talks revolve around the idea of cross-platform data integration, discussing processes and solutions for rapidly developing an integrated workflow across independent systems for the US BRAIN Initiative Cell Census. 

 
INCF TrainingSpace

Introduction to Deep Learning

NYU Center for Data Science

This module provides an introduction to the motivation of deep learning and its history and inspiration.

 

Ethics and Governance

Ethical conduct of science, good governance of data, and accelerated translation to the clinic are key to high-calibre open neuroscience.  Everyday practitioners of science must be sensitized to a range of ethical considerations in their research, some having especially to do with open data-sharing. The lessons included in this course introduce a number of these topics and end with concrete guidance for participant consent and de-identification of data.

 

INCF Assembly 2022 - Day 3 Sessions

INCF

Sessions from the INCF Neuroinformatics Assembly 2022 Day 3. 

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