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Applied Ethics in Machine Learning and Mental Health

Krembil Centre for Neuroinformatics

This course tackles the issue of maintaining ethical research and healthcare practices in the age of increasingly powerful technological tools like machine learning and artificial intelligence. While there is great potential for innovation and improvement in the clinical space thanks to AI development, lecturers in this course advocate for a greater emphasis on human-centric care, calling for algorithm design which takes the full intersectionality of individuals into account.

 

Data Science and Neuroinformatics

INCF

Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools.

 

Whole-Brain Modelling

Krembil Centre for Neuroinformatics

Given the extreme interconnectedness of the human brain, studying any one cerebral area in isolation may lead to spurious results or incomplete, if not problematic, interpretations. This course introduces participants to the various spatial scales of neuroscience and the fundamentals of whole-brain modelling, used to generate a more thorough picture of brain activity.

 

FAIR neuroscience and EBRAINS tools for data sharing, analysis, and simulation

INCF

This workshop provides an opportunity to explore the advanced tools and techniques for data sharing, analysis, visualization, and simulation.

 

Neuroimaging Connectomics

Krembil Centre for Neuroinformatics

This course consists of one lesson and one tutorial, focusing on the neural connectivity measures derived from neuroimaging, specifically from methods like functional magnetic resonance imaging (fMRI) and diffusion-weighted imaging (DWI). Additional tools such as tractography and parcellation are discussed in the context of brain connectivity and mental health. The tutorial leads participants through the computation of brain connectomes from fMRI data. 

 

INCF Assembly 2022 - Training Day 2

INCF

This course contains sessions from the second day of INCF's Neuroinformatics Assembly 2022.

 

Simulating Brain Microcircuit Activity and Signals in Mental Health

Krembil Centre for Neuroinformatics

This course offers lectures on the origin and functional significance of certain electrophysiological signals in the brain, as well as a hands-on tutorial on how to simulate, statistically evaluate, and visualize such signals. Participants will learn the simulation of signals at different spatial scales, including single-cell (neuronal spiking) and global (EEG), and how these may serve as biomarkers in the evaluation of mental health data.

 

Introductory Concepts

Krembil Centre for Neuroinformatics

This couse is the opening module for the University of Toronto's Krembil Centre for Neuroinformatics' virtual learning series Solving Problems in Mental Health Using Multi-Scale Computational Neuroscience. Lessons in this course introduce participants to the study of brain disorders, starting from elemental units like genes and neurons, eventually building up to whole-brain modelling and global activity patterns.

 

FAIR neuroscience and EBRAINS tools for data sharing, analysis, and simulation

INCF

This workshop provides an opportunity to explore the advanced tools and techniques for data sharing, analysis, visualization, and simulation.

 

Fundamental Methods for Single-Cell Transcriptome Analysis

Krembil Centre for Neuroinformatics

This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression). 

 

Open Data in Neuroscience: Data Sharing in EBRAINS

Maaike van Swieten, Ida Aasebø, the EBRAINS curation services and HBP-EBRAINS

There is a broad consensus among researchers, publishers, and funding bodies that open sharing of data is needed to address major reproducibility and transparency challenges that currently exist in all scientific disciplines. In addition to potentially increasing the utilization of shared data through re-analysis and integration with other data, data sharing is beneficial for individual researchers through data citation and increased exposure of research.

 

Digital Health for Mental Health

Krembil Centre for Neuroinformatics

As technological improvements continue to facilitate innovations in the mental health space, researchers and clinicians are faced with novel opportunities and challenges regarding study design, diagnoses, treatments, and follow-up care. This course includes a lecture outlining these new developments, as well as a workshop which introduces users to Synapse, an open-source platform for collaborative data analysis. 

 

Simulating Brain Microcircuit Activity and Signals in Mental Health

Krembil Centre for Neuroinformatics

This course offers lectures on the origin and functional significance of certain electrophysiological signals in the brain, as well as a hands-on tutorial on how to simulate, statistically evaluate, and visualize such signals. Participants will learn the simulation of signals at different spatial scales, including single-cell (neuronal spiking) and global (EEG), and how these may serve as biomarkers in the evaluation of mental health data.

 

Module 3: Computational Models

Mike X. Cohen

This module introduces computational neuroscience by simulating neurons according to the AdEx model. You will learn about generative modeling, dynamical systems, and F-I curves. The MATLAB code introduces live scripts and functions.

 

Bayesian Statistics

Neuromatch Academy

Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.

 

Module 5: Calcium Imaging

Mike X. Cohen

In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.

 

INCF Assembly 2022 - Training Day 1

INCF

This course contains sessions from the first day of INCF's Neuroinformatics Assembly 2022.

 
INCF TrainingSpace

Session 7: Practical Guide to Overcome the Reproducibility Crisis in Small Animal Neuroimaging: Workflows, Tools, and Repositories

INCF

The workshop will include interactive seminars given by selected experts in the field covering all aspects of (FAIR) small animal MRI data acquisition, analysis, and sharing. The seminars will be followed by hands-on training where participants will perform use case scenarios using software established by the organizers. This will include an introduction to the basics of using command line interfaces, Python installation, working with Docker/Singularity containers, Datalad/Git, and BIDS.

 
INCF TrainingSpace

Preprocessing Data in EEGLAB

Swartz Center for Computational Neuroscience

EEGLAB is an interactive MATLAB toolbox for processing continuous and event-related EEG, MEG, and other electrophysiological data incorporating independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data.

 

Fundamental Methods for Single-Cell Transcriptome Analysis

Krembil Centre for Neuroinformatics

This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression).