This course contains videos, lectures, and hands-on tutorials as part of INCF's Neuroinformatics Assembly 2023 workshop on developing robust and reproducible research workflows to foster greater collaborative efforts in neuroscience.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and remaining barriers.
Sessions from the INCF Neuroinformatics Assembly 2022 Day 3.
This course consists of one lesson and one tutorial, focusing on the neural connectivity measures derived from neuroimaging, specifically from methods like functional magnetic resonance imaging (fMRI) and diffusion-weighted imaging (DWI). Additional tools such as tractography and parcellation are discussed in the context of brain connectivity and mental health. The tutorial leads participants through the computation of brain connectomes from fMRI data.
This workshop provides basic knowledge on personalized brain network modeling using the open-source simulation platform The Virtual Brain (TVB). Participants will gain theoretical knowledge and apply this knowledge to construct brain models, process multimodal neuroimaging data for reconstructing individual brains, run simulations, and use supporting neuroinformatics tools such as collaboratories, pipelines, workflows, and data repositories.
This course provides several visual walkthroughs documenting how to execute various processes in brainlife.io, an open-source, free and secure reproducible neuroscience analysis platform. The platform allows to analyze Magnetic Resonance Imaging (MRI), electroencephalography (EEG) and magnetoencephalography (MEG) data. Data can either be uploaded from local computers or imported from public archives such as OpenNeuro.org.
This course consists of two workshops which focus on the need for reproducibility in science, particularly under the umbrella roadmap of FAIR scienctific principles. The tutorials also provide an introduction to some of the most commonly used open-source scientific tools, including Git, GitHub, Google Colab, Binder, Docker, and the programming languages Python and R.
Most approaches within computational neuroscience simulate systems, brain networks, local circuits, as they are now. In recent years, homeostatic regulation has been characterized and modeled; however, for understanding diseases that have their origin in genetic defects that emerge at later age, it is important to understand how these defects interact with developmental processes that occur earlier and last longer that the typical period considered for homeostatic studies.
This course corresponds to the third session of talks given at INCF's Neuroinformatics Assembly 2023. In this session, the talks revolve around the idea of cross-platform data integration, discussing processes and solutions for rapidly developing an integrated workflow across independent systems for the US BRAIN Initiative Cell Census.
In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.
The UCSC Genome Browser is an online and downloadable genome browser hosted by the University of California, Santa Cruz (UCSC). It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations.
Neuromatch Academy aims to introduce traditional and emerging tools of computational neuroscience to trainees.
Future computing systems will capitalize on our increased understanding of the brain through the use of similar architectures and computational principles. During this workshop, we bring together recent developments in this rapidly developing field of neuromorphic computing systems, and also discuss challenges ahead.
This course tackles the issue of maintaining ethical research and healthcare practices in the age of increasingly powerful technological tools like machine learning and artificial intelligence. While there is great potential for innovation and improvement in the clinical space thanks to AI development, lecturers in this course advocate for a greater emphasis on human-centric care, calling for algorithm design which takes the full intersectionality of individuals into account.
Over the last three decades, neuroimaging research has seen large strides in the scale, diversity, and complexity of studies, the open availability of data and methodological resources, the quality of instrumentation and multimodal studies, and the number of researchers and consortia. The awareness of rigor and reproducibility has increased with the advent of funding mandates, and with the work done by national and international brain initiatives.
In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.
This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression).
This course corresponds to the second session of INCF's Neuroinformatics Assembly 2023. This series of talks continues a discussion of FAIR principles from the first session, with a greater emphasis on brain data (humans and animals) atlases for data analysis and integation.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and remaining barriers.
This module introduces computational neuroscience by simulating neurons according to the AdEx model. You will learn about generative modeling, dynamical systems, and F-I curves. The MATLAB code introduces live scripts and functions.