This lecture covers the history of behaviorism and the ultimate challenge to behaviorism.
In this lesson, you will learn how to utilize various features and tools included in the EBRAINS platform, particularly focusing on rodent brain atlases and how to incorporate them into your analyses.
This talk describes how to use DataLad for your data management and curation techniques when dealing with animal datasets, which often contain several disparate types of data, including MRI, microscopy, histology, electrocorticography, and behavioral measurements.
In this short talk you will learn about The Neural System Laboratory, which aims to develop and implement new technologies for analysis of brain architecture, connectivity, and brain-wide gene and molecular level organization.
In this lesson, you will learn about the connectome, the collective system of neural pathways in an organism, with a closer look at the neurons, synapses, and connections of particular species.
This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system.
In this lecture, attendees will learn how Mutant Mouse Resource and Research Center (MMRRC) archives, cryopreserves, and distributes scientifically valuable genetically engineered mouse strains and mouse ES cell lines for the genetics and biomedical research community.
This lecture discusses how to standardize electrophysiology data organization to move towards being more FAIR.
This lecture covers visualizing extracellular neurotransmitter dynamics
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?
This lecture consists of the second half of the introduction to signal transduction, here focusing on cell receptors and signalling cascades.
In this lesson, you will learn about GABAergic interneurons and local inhibition on the circuit level.
This lecture explains the concept of federated analysis in the context of medical data, associated challenges. The lecture also presents an example of hospital federations via the Medical Informatics Platform.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.