This lecture provides an overview of successful open-access projects aimed at describing complex neuroscientific models, and makes a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
This lecture provides an introduction to the Brain Imaging Data Structure (BIDS), a standard for organizing human neuroimaging datasets.
This lesson provides an overview of Neurodata Without Borders (NWB), an ecosystem for neurophysiology data standardization. The lecture also introduces some NWB-enabled tools.
This lesson outlines Neurodata Without Borders (NWB), a data standard for neurophysiology which provides neuroscientists with a common standard to share, archive, use, and build analysis tools for neurophysiology data.
This lecture covers the rationale for developing the DAQCORD, a framework for the design, documentation, and reporting of data curation methods in order to advance the scientific rigour, reproducibility, and analysis of data.
This tutorial demonstrates how to use PyNN, a simulator-independent language for building neuronal network models, in conjunction with the neuromorphic hardware system SpiNNaker.
This lecture explains the concept of federated analysis in the context of medical data, associated challenges. The lecture also presents an example of hospital federations via the Medical Informatics Platform.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
In this lecture, you will learn about current methods, approaches, and challenges to studying human neuroanatomy, particularly through the lense of neuroimaging data such as fMRI and diffusion tensor imaging (DTI).
This lesson provides a thorough description of neuroimaging development over time, both conceptually and technologically. You will learn about the fundamentals of imaging techniques such as MRI and PET, as well as how the resultant data may be used to generate novel data visualization schemas.
This lecture covers a wide range of aspects regarding neuroinformatics and data governance, describing both their historical developments and current trajectories. Particular tools, platforms, and standards to make your research more FAIR are also discussed.
As the previous lesson of this course described how researchers acquire neural data, this lesson will discuss how to go about interpreting and analysing the data.
This lesson gives a quick walkthrough the Tidyverse, an "opinionated" collection of R packages designed for data science, including the use of readr, dplyr, tidyr, and ggplot2.
In this session the Medical Informatics Platform (MIP) federated analytics is presented. The current and future analytical tools implemented in the MIP will be detailed along with the constructs, tools, processes, and restrictions that formulate the solution provided. MIP is a platform providing advanced federated analytics for diagnosis and research in clinical neuroscience research. It is targeting clinicians, clinical scientists and clinical data scientists. It is designed to help adopt advanced analytics, explore harmonized medical data of neuroimaging, neurophysiological and medical records as well as research cohort datasets, without transferring original clinical data. It can be perceived as a virtual database that seamlessly presents aggregated data from distributed sources, provides access and analyze imaging and clinical data, securely stored in hospitals, research archives and public databases. It leverages and re-uses decentralized patient data and research cohort datasets, without transferring original data. Integrated statistical analysis tools and machine learning algorithms are exposed over harmonized, federated medical data.
The Medical Informatics Platform (MIP) is a platform providing federated analytics for diagnosis and research in clinical neuroscience research. The federated analytics is possible thanks to a distributed engine that executes computations and transfers information between the members of the federation (hospital nodes). In this talk the speaker will describe the process of designing and implementing new analytical tools, i.e. statistical and machine learning algorithms. Mr. Sakellariou will further describe the environment in which these federated algorithms run, the challenges and the available tools, the principles that guide its design and the followed general methodology for each new algorithm. One of the most important challenges which are faced is to design these tools in a way that does not compromise the privacy of the clinical data involved. The speaker will show how to address the main questions when designing such algorithms: how to decompose and distribute the computations and what kind of information to exchange between nodes, in order to comply with the privacy constraint mentioned above. Finally, also the subject of validating these federated algorithms will be briefly touched.