This lesson gives an introduction to high-performance computing with the Compute Canada network, first providing an overview of use cases for HPC and then a hands-on tutorial. Though some examples might seem specific to the Calcul Québec, all computing clusters in the Compute Canada network share the same software modules and environments.

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

This lesson provides an introduction to the lifecycle of EEG/ERP data, describing the various phases through which these data pass, from collection to publication.

In this lesson you will learn about experimental design for EEG acquisition, as well as the first phases of the EEG/ERP data lifecycle. 

This lesson provides an overview of the current regulatory measures in place regarding experimental data security and privacy. 

In this lesson, you will learn the appropriate methods for collection of both data and associated metadata during EEG experiments.

This lesson goes over methods for managing EEG/ERP data after it has been collected, from annotation to publication. 

In this final lesson of the course, you will learn broadly about EEG signal processing, as well as specific applications which make this kind of brain signal valuable to researchers and clinicians. 

This lecture contains an overview of the Australian Electrophysiology Data Analytics Platform (AEDAPT), how it works, how to scale it, and how it fits into the FAIR ecosystem.

This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

In this lesson, you will learn about how genetics can contribute to our understanding of psychiatric phenotypes.

This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity. 

This lesson describes a definitional framework for fairness and health equity in the age of the algorithm. While acknowledging the impressive capability of machine learning to positively affect health equity, this talk outlines potential (and actual) pitfalls which come with such powerful tools, ultimately making the case for collaborative, interdisciplinary, and transparent science as a way to operationalize fairness in health equity. 

This lecture covers multiple aspects of FAIR neuroscience data: what makes it unique, the challenges to making it FAIR, the importance of overcoming these challenges, and how data governance comes into play.

This lecture provides guidance on the ethical considerations the clinical neuroimaging community faces when applying the FAIR principles to their research.