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Introduction to nociceptors and perception of pain

Difficulty level

This lecture focuses on the comprehension of nociception and pain sensation. It highlights how the somatosensory system and different molecular partners are involved in nociception and how nociception and pain sensation are studied in rodents and humans and the development of pain therapy.

Topics covered in this lesson
  1. Nociception vs. pain
  2. How nociception works and how a nociceptor is defined
  3. Characteristics of nerve fibers and dorsal root ganglia
  4. How to test nociception: Methods available for rodents and humans
  5. Types of pain and pain models
  6. Pain pathways and important molecular partners (neurotransmitters, cytokines, growth factors and channels)
  7. Specific pain syndromes and pain therapy