This couse is the opening module for the University of Toronto's Krembil Centre for Neuroinformatics' virtual learning series Solving Problems in Mental Health Using Multi-Scale Computational Neuroscience. Lessons in this course introduce participants to the study of brain disorders, starting from elemental units like genes and neurons, eventually building up to whole-brain modelling and global activity patterns.

This course consists of several introductory lectures on different aspects of biochemical models. The lectures cover topics such as stability analysis of neural models, oscillations and bursting, and weakly coupled oscillators. You will learn about modeling various scales and properties of neural mechanisms, from firing-rate models of single neurons to pattern generation in visual system hallucinations. 

Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools.

The CAJAL Course in Computational Neuroscience teaches the central ideas, methods, and practice of modern computational neuroscience through a combination of lectures and hands-on project work. This course is designed for graduate students and postdoctoral fellows from a variety of disciplines, including neuroscience, physics, electrical engineering, computer science, mathematics, and psychology. 

This workshop is organized by the German National Research Data Infrastructure Initiative Neuroscience (NFDI-Neuro). The initiative is community driven and comprises around 50 contributing national partners and collaborators. NFDI-Neuro partners with EBRAINS AISB, the coordinating entity of the EU Human Brain Project and the EBRAINS infrastructure. We will introduce common methods that enable digital reproducible neuroscience.

In this course we present the TVB-EBRAINS integrated workflows that have been developed in the Human Brain Project in the third funding phase (“SGA2”) in the Co-Design Project 8 “The Virtual Brain”. 

This course, consisting of one lecture and two workshops, is presented by the Computational Genomics Lab at the Centre for Addiction and Mental Health and University of Toronto. The lecture deals with single-cell and bulk level transciptomics, while the two hands-on workshops introduce users to transcriptomic data types (e.g., RNAseq) and how to perform analyses in specific use cases (e.g., cellular changes in major depression). 

The Neurodata Without Borders: Neurophysiology project (NWB:N, https://www.nwb.org/) is an effort to standardize the description and storage of neurophysiology data and metadata. NWB enables data sharing and reuse and reduces the energy barrier to applying data analytics both within and across labs. Several laboratories, including the Allen Institute for Brain Science, have wholeheartedly adopted NWB.

This course is intended for those interested in electroencephalography (EEG) and event-related potentials (ERPs) techniques, and those interested in collecting, annotating, standardizing, storing, processing, sharing, and publishing data from electrical activity of the human brain.

A number of programming languages are ubiquitous in modern neuroscience and are key to the competence, freedom, and creativity necessary in neuroscience research. This course offers lectures on the fundamentals of data science and specific neuroinformatic tools used in the investigation of brain data. Attendees of this course will be learn about the programming languages Python, R, and MATLAB, as well as their associated packages and software environments. 

The emergence of data-intensive science creates a demand for neuroscience educators worldwide to deliver better neuroinformatics education and training in order to raise a generation of modern neuroscientists with FAIR capabilities, awareness of the value of standards and best practices, knowledge in dealing with big datasets, and the ability to integrate knowledge over multiple scales and methods.

This course consists of a three-part session from the second day of INCF's Neuroinformatics Assembly 2023. The lessons describe various on-going efforts within the fields of neuroinformatics and clinical neuroscience to adjust to the increasingly vast volumes of brain data being collected and stored.

This module covers fMRI data, including creating and interpreting flatmaps, exploring variability and average responses, and visual eccenticity. You will learn about processing BOLD signals, trial-averaging, and t-tests. The MATLAB code introduces data animations, multicolor visualizations, and linear indexing.

Notebook systems are proving invaluable to skill acquisition, research documentation, publication, and reproducibility.  This series of presentations introduces the most popular platform for computational notebooks, Project Jupyter, as well as other resources like Binder and NeuroLibre. 

Most neuroscience journals request authors to make their data publicly available in appropriate repositories. The requirements and policies put forward by journals vary, and the services provided for different types of data also differ considerably across repositories.

As technological improvements continue to facilitate innovations in the mental health space, researchers and clinicians are faced with novel opportunities and challenges regarding study design, diagnoses, treatments, and follow-up care. This course includes a lecture outlining these new developments, as well as a workshop which introduces users to Synapse, an open-source platform for collaborative data analysis. 

The dimensionality and size of datasets in many fields of neuroscience research require massively parallel computing power.  Fortunately, the maturity and accessibility of virtualization technologies has made it feasible to run the same analysis environments on platforms ranging from single laptop computers up to high-performance computing networks.

EEGLAB is an interactive MATLAB toolbox for processing continuous and event-related EEG, MEG, and other electrophysiological data. In this course, you will learn about features incorporated into EEGLAB, including independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data. EEGLAB runs under Linux, Unix, Windows, and Mac OS X.

The emergence of data-intensive science creates a demand for neuroscience educators worldwide to deliver better neuroinformatics education and training in order to raise a generation of modern neuroscientists with FAIR capabilities, awareness of the value of standards and best practices, knowledge in dealing with big datasets, and the ability to integrate knowledge over multiple scales and methods.

Most who enter the field of computational neuroscience have a prior background in either mathematics, physics, computer science, or (neuro)biology. Since computational neuroscience requires a bit of knowledge from all these fields, with some basic knowledge of neurons and a familiarity with certain types of equations and mathematical concepts, we recommend two different "starting tracks" depending on the student's background before you begin the lectures listed below: