In this course, we introduce transcranial ultrasonic stimulation (TUS) to those who are new to the field of non-invasive brain stimulation (NIBS). We will explain what TUS can be used for, in the context of biomedical and research applications of ultrasound, illustrated using example studies. Additionally, we provide a brief history of the technique and a broad introduction to the biophysics of TUS.
TUS – sneak peek
Course Features
Introduction to Transcranial Ultrasonic Stimulation (TUS) in the context of Non-Invasive Brain Stimulation (NIBS).
Explanation of TUS applications in biomedical and research settings, with example studies.
Brief history of TUS technique.
Broad introduction to the biophysics of TUS.
Lessons of this Course
1
1
Duration:
19:32
Speaker:
Overview of transcranial ultrasonic stimulation (TUS). TUS is introduced in the context of the wide range of biomedical applications of ultrasound, followed by a brief description of the underlying mechanisms, effects and applications of TUS. The goal of this lecture is to provide an introduction for an audience with no previous knowledge or experience of TUS.
At the end of this lecture, students will be able to briefly summarize the underlying mechanisms and effects of TUS, and contrast them with other biomedical applications of ultrasound.
2
2
Duration:
23:57
Speaker:
Overview of transcranial ultrasonic stimulation (TUS). TUS is introduced in the context of the wide range of biomedical applications of ultrasound, followed by a brief description of the underlying mechanisms, effects and applications of TUS. The goal of this lecture is to provide an introduction for an audience with no previous knowledge or experience of TUS.
At the end of this lecture, students will be able to briefly summarize the underlying mechanisms and effects of TUS, and contrast them with other biomedical applications of ultrasound.
3
3
Duration:
12:07
Speaker:
This lecture covers the basic neurophysiology and biomechanisms of TUS. Some basic neurophysiological processes, including action potentials and plasticity, are summarised as a basis for discussing the potential mechanisms through which TUS interacts with these neurophysiological processes. The goal of this lecture is to introduce the audience to the ways in which the biophysical interactions between ultrasound and neurophysiology can lead to neuromodulation.
At the end of this lecture, students will be able to explain some of the mechanisms through which ultrasound can interact with neurons and glial cells, and lead to neuromodulatory and neuroplastic effects.
4
4
Duration:
11:47
Speaker:
TUS can have a variety of effects and can therefore we used for many different basic science and clinical applications. One way to tune the effects is to modify the application protocols. The goal of this lecture is to introduce students to the TUS parameters which encompass a protocol, and use examples from the literature to illustrate the effects of some protocols.
At the end of this lecture, students will be able to define the parameters that encompass a TUS protocol, and illustrate how they relate to the effects using examples from the literature. keywords: TUS parameters, transcranial ultrasonic stimulation, online effects, offline effects
