In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.

In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.

This course features tutorials on how to use Allen atlases and digital brain atlasing tools, including operational and user features of the Allen Mouse Brain Atlas, as well as the Allen Institute's 3D viewing tool, Brain Explorer®.

In this course we present the TVB-EBRAINS integrated workflows that have been developed in the Human Brain Project in the third funding phase (“SGA2”) in the Co-Design Project 8 “The Virtual Brain”. 

As technological improvements continue to facilitate innovations in the mental health space, researchers and clinicians are faced with novel opportunities and challenges regarding study design, diagnoses, treatments, and follow-up care. This course includes a lecture outlining these new developments, as well as a workshop which introduces users to Synapse, an open-source platform for collaborative data analysis. 

The dimensionality and size of datasets in many fields of neuroscience research require massively parallel computing power.  Fortunately, the maturity and accessibility of virtualization technologies has made it feasible to run the same analysis environments on platforms ranging from single laptop computers up to high-performance computing networks.

This course outlines how versioning code, data, and analysis software is crucially important to rigorous and open neuroscience workflows that maximize reproducibility and minimize errors.Version control systems, code-capable notebooks, and virtualization containers such as Git, Jupyter, and Docker, respectively, have become essential tools in data science.

As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and remaining barriers.

This course consists of one lesson and one tutorial, focusing on the neural connectivity measures derived from neuroimaging, specifically from methods like functional magnetic resonance imaging (fMRI) and diffusion-weighted imaging (DWI). Additional tools such as tractography and parcellation are discussed in the context of brain connectivity and mental health. The tutorial leads participants through the computation of brain connectomes from fMRI data. 

As research methods and experimental technologies become ever more sophisticated, the amount of health-related data per individual which has become accessible is vast, giving rise to a corresponding need for cross-domain data integration, whole-person modelling, and improved precision medicine. This course provides lessons describing state of the art methods and repositories, as well as a tutorial on computational methods for data integration. 

This course consists of introductory lectures on different aspects of biophysical models. By following this course you will learn about various neuronal models, neuron anatomy and signaling, as well the numerous and complex cellular mechanisms underlying healthy brain function. 

This course offers lectures on the origin and functional significance of certain electrophysiological signals in the brain, as well as a hands-on tutorial on how to simulate, statistically evaluate, and visualize such signals. Participants will learn the simulation of signals at different spatial scales, including single-cell (neuronal spiking) and global (EEG), and how these may serve as biomarkers in the evaluation of mental health data.

This course consists of two workshops which focus on the need for reproducibility in science, particularly under the umbrella roadmap of FAIR scienctific principles. The tutorials also provide an introduction to some of the most commonly used open-source scientific tools, including Git, GitHub, Google Colab, Binder, Docker, and the programming languages Python and R. 

Neuroanatomy provides one of the unifying frameworks for neuroscience and thus it is not surprising that it provides the basis for many neuroinformatics tools and approaches.  Regardless of whether one is working at the subcellular, cellular or gross anatomical level or whether one is modeling circuitry, molecular pathways or function, at some point, this work will include an anatomical reference.

This couse is the opening module for the University of Toronto's Krembil Centre for Neuroinformatics' virtual learning series Solving Problems in Mental Health Using Multi-Scale Computational Neuroscience. Lessons in this course introduce participants to the study of brain disorders, starting from elemental units like genes and neurons, eventually building up to whole-brain modelling and global activity patterns.

Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools.

Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools.

This course tackles the issue of maintaining ethical research and healthcare practices in the age of increasingly powerful technological tools like machine learning and artificial intelligence. While there is great potential for innovation and improvement in the clinical space thanks to AI development, lecturers in this course advocate for a greater emphasis on human-centric care, calling for algorithm design which takes the full intersectionality of individuals into account.

Given the extreme interconnectedness of the human brain, studying any one cerebral area in isolation may lead to spurious results or incomplete, if not problematic, interpretations. This course introduces participants to the various spatial scales of neuroscience and the fundamentals of whole-brain modelling, used to generate a more thorough picture of brain activity.