This book was written with the goal of introducing researchers and students in a variety of research fields to the intersection of data science and neuroimaging. This book reflects our own experience of doing research at the intersection of data science and neuroimaging and it is based on our experience working with students and collaborators who come from a variety of backgrounds and have a variety of reasons for wanting to use data science approaches in their work. The tools and ideas that we chose to write about are all tools and ideas that we have used in some way in our own research. Many of them are tools that we use on a daily basis in our work. This was important to us for a few reasons: the first is that we want to teach people things that we ourselves find useful. Second, it allowed us to write the book with a focus on solving specific analysis tasks. For example, in many of the chapters you will see that we walk you through ideas while implementing them in code, and with data. We believe that this is a good way to learn about data analysis, because it provides a connecting thread from scientific questions through the data and its representation to implementing specific answers to these questions. Finally, we find these ideas compelling and fruitful. That’s why we were drawn to them in the first place. We hope that our enthusiasm about the ideas and tools described in this book will be infectious enough to convince the readers of their value.

This talk gives an overview of the Human Brain Project, a 10-year endeavour putting in place a cutting-edge research infrastructure that will allow scientific and industrial researchers to advance our knowledge in the fields of neuroscience, computing, and brain-related medicine.

This lecture gives an introduction to the European Academy of Neurology, its recent achievements and ambitions.

This talk enumerates the challenges regarding data accessibility and reusability inherent in the current scientific publication system, and discusses novel approaches to these challenges, such as the EBRAINS Live Papers platform. 

This lesson aims to define computational neuroscience in general terms, while providing specific examples of highly successful computational neuroscience projects. 

This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level. 

In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.

This lesson discusses voltage-gating kinetics of sodium and potassium channels.

In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

This lesson delves into the specifics of how action potentials propagate through individual neurons.

This lesson discusses long-range inhibitory connections in the brain, with examples from three different systems.

An introduction to data management, manipulation, visualization, and analysis for neuroscience. Students will learn scientific programming in Python, and use this to work with example data from areas such as cognitive-behavioral research, single-cell recording, EEG, and structural and functional MRI. Basic signal processing techniques including filtering are covered. The course includes a Jupyter Notebook and video tutorials.

This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health. 

This tutorial introduces pipelines and methods to compute brain connectomes from fMRI data. With corresponding code and repositories, participants can follow along and learn how to programmatically preprocess, curate, and analyze functional and structural brain data to produce connectivity matrices. 

In this lesson, you will learn about the connectome, the collective system of neural pathways in an organism, with a closer look at the neurons, synapses, and connections of particular species. 

This lesson delves into the human nervous system and the immense cellular, connectomic, and functional sophistication therein. 

In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?

The "connectome" is a term, coined in the past decade, that has been used to describe more than one phenomenon in neuroscience. This lecture explains the basics of structural connections at the micro-, meso- and macroscopic scales.

This talk covers the Human Connectome Project, which aims to provide an unparalleled compilation of neural data, an interface to graphically navigate this data, and the opportunity to achieve never before realized conclusions about the living human brain.

EyeWire is a game to map the brain. Players are challenged to map branches of a neuron from one side of a cube to the other in a 3D puzzle. Players scroll through the cube and reconstruct neurons with the help of an artificial intelligence algorithm developed at Seung Lab in Princeton University. EyeWire gameplay advances neuroscience by helping researchers discover how neurons connect to process visual information.