Most approaches within computational neuroscience simulate systems, brain networks, local circuits, as they are now. In recent years, homeostatic regulation has been characterized and modeled; however, for understanding diseases that have their origin in genetic defects that emerge at later age, it is important to understand how these defects interact with developmental processes that occur earlier and last longer that the typical period considered for homeostatic studies.
This workshop delves into the need for, structure of, tools for, and use of hierarchical event descriptor (HED) annotation to prepare neuroimaging time series data for storing, sharing, and advanced analysis. HED are a controlled vocabulary of terms describing events in a machine-actionable form so that algorithms can use the information without manual recoding.
This course consists of three lessons, each corresponding to a lightning talk given at the first day of INCF's Neuroinformatics Assembly 2023. By following along these brief talks, you will hear about topics such as open source tools for computer vision, tools for the integration of various MRI dataset formats, as well as international data governance.
This couse is the opening module for the University of Toronto's Krembil Centre for Neuroinformatics' virtual learning series Solving Problems in Mental Health Using Multi-Scale Computational Neuroscience. Lessons in this course introduce participants to the study of brain disorders, starting from elemental units like genes and neurons, eventually building up to whole-brain modelling and global activity patterns.
This course contains sessions from the first day of INCF's Neuroinformatics Assembly 2022.
This module introduces computational neuroscience by simulating neurons according to the AdEx model. You will learn about generative modeling, dynamical systems, and F-I curves. The MATLAB code introduces live scripts and functions.
Ethical conduct of science, good governance of data, and accelerated translation to the clinic are key to high-calibre open neuroscience. Everyday practitioners of science must be sensitized to a range of ethical considerations in their research, some having especially to do with open data-sharing. The lessons included in this course introduce a number of these topics and end with concrete guidance for participant consent and de-identification of data.
This course contains sessions from the second day of INCF's Neuroinformatics Assembly 2022.
Probing the organization of interactions within and across neuronal populations is a promising approach to understanding the principles of brain processing. The rapidly advancing technical capabilities to record from hundreds of neurons in parallel open up new possibilities to disentangle the correlative structure within neuronal networks. However, the complexity of these massive data streams calls for novel, tractable analysis tools that exploit the parallel aspect of the data.
As research methods and experimental technologies become ever more sophisticated, the amount of health-related data per individual which has become accessible is vast, giving rise to a corresponding need for cross-domain data integration, whole-person modelling, and improved precision medicine. This course provides lessons describing state of the art methods and repositories, as well as a tutorial on computational methods for data integration.
Bayesian inference (using prior knowledge to generate more accurate predictions about future events or outcomes) has become increasingly applied to the fields of neuroscience and neuroinformatics. In this course, participants are taught how Bayesian statistics may be used to build cognitive models of processes like learning or perception. This course also offers theoretical and practical instruction on dynamic causal modeling as applied to fMRI and EEG data.
A number of programming languages are ubiquitous in modern neuroscience and are key to the competence, freedom, and creativity necessary in neuroscience research. This course offers lectures on the fundamentals of data science and specific neuroinformatic tools used in the investigation of brain data. Attendees of this course will be learn about the programming languages Python, R, and MATLAB, as well as their associated packages and software environments.
This course consists of two workshops which focus on the need for reproducibility in science, particularly under the umbrella roadmap of FAIR scienctific principles. The tutorials also provide an introduction to some of the most commonly used open-source scientific tools, including Git, GitHub, Google Colab, Binder, Docker, and the programming languages Python and R.
In this short series of lectures, participants will take a look at articles using TVB in a clinical context. Specifically, participants will see how TVB can help to predict recovery after stroke and how individual epileptic seizures are simulated. The course lecturers will briefly describe the methods used and results achieved in the articles.
There is a broad consensus among researchers, publishers, and funding bodies that open sharing of data is needed to address major reproducibility and transparency challenges that currently exist in all scientific disciplines. In addition to potentially increasing the utilization of shared data through re-analysis and integration with other data, data sharing is beneficial for individual researchers through data citation and increased exposure of research.
Most who enter the field of computational neuroscience have a prior background in either mathematics, physics, computer science, or (neuro)biology. Since computational neuroscience requires a bit of knowledge from all these fields, with some basic knowledge of neurons and a familiarity with certain types of equations and mathematical concepts, we recommend two different "starting tracks" depending on the student's background before you begin the lectures listed below:
This workshop provides an opportunity to explore the advanced tools and techniques for data sharing, analysis, visualization, and simulation.
The International Brain Initiative (IBI) is a consortium of the world’s major large-scale brain initiatives and other organizations with a vested interest in catalyzing and advancing neuroscience research through international collaboration and knowledge sharing. This session will introduce the IBI and the current efforts of the Data Standards and Sharing Working Group with a view to gain input from a wider neuroscience and neuroinformatics community.
The CAJAL Course in Computational Neuroscience teaches the central ideas, methods, and practice of modern computational neuroscience through a combination of lectures and hands-on project work. This course is designed for graduate students and postdoctoral fellows from a variety of disciplines, including neuroscience, physics, electrical engineering, computer science, mathematics, and psychology.
In this course, you will learn about working with calcium-imaging data, including image processing to remove background "blur", identifying cells based on threshold spatial contiguity, time-series filtering, and principal component analysis (PCA). The MATLAB code shows data animations, capabilities of the image processing toolbox, and PCA.