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This lesson continues from part one of the lecture Ontologies, Databases, and Standards, diving deeper into a description of ontologies and knowledg graphs. 

Difficulty level: Intermediate
Duration: 50:18
Speaker: : Jeff Grethe

This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.

Difficulty level: Beginner
Duration: 14:24
Speaker: : Heidi Kleven

This lecture focuses on ontologies for clinical neurosciences.

Difficulty level: Intermediate
Duration: 21:54

This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves. 

Difficulty level: Intermediate
Duration: 8:21
Speaker: : Mike X. Cohen

In this lesson, users learn how to use MATLAB to build an adaptive exponential integrate and fire (AdEx) neuron model. 

Difficulty level: Intermediate
Duration: 22:01
Speaker: : Mike X. Cohen

In this lesson, users learn about the practical differences between MATLAB scripts and functions, as well as how to embed their neuronal simulation into a callable function.  

Difficulty level: Intermediate
Duration: 11:20
Speaker: : Mike X. Cohen

This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F). 

Difficulty level: Intermediate
Duration: 20:39
Speaker: : Mike X. Cohen

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

Difficulty level: Beginner
Duration: 2:24:35

This lesson aims to define computational neuroscience in general terms, while providing specific examples of highly successful computational neuroscience projects. 

Difficulty level: Beginner
Duration: 59:21
Speaker: : Alla Borisyuk

This lesson introduces some practical exercises which accompany the Synapses and Networks portion of this Neuroscience for Machine Learners course. 

Difficulty level: Intermediate
Duration: 3:51
Speaker: : Dan Goodman

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

Difficulty level: Intermediate
Duration: 12:50
Speaker: : Dan Goodman

 In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way. 

Difficulty level: Intermediate
Duration: 5:14
Speaker: : Dan Goodman

In this lesson, you will learn how to train spiking neural networks (SNNs) with a surrogate gradient method. 

Difficulty level: Intermediate
Duration: 11:23
Speaker: : Dan Goodman

In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?

Difficulty level: Intermediate
Duration: 6:54
Speaker: : Marcus Ghosh

This lecture covers an Introduction to neuron anatomy and signaling, and different types of models, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 1:23:01
Speaker: : Gaute Einevoll

The Virtual Brain (TVB) is an open-source, multi-scale, multi-modal brain simulation platform. In this lesson, you get introduced to brain simulation in general and to TVB in particular. This lesson also presents the newest approaches for clinical applications of TVB - that is, for stroke, epilepsy, brain tumors, and Alzheimer’s disease - and show how brain simulation can improve diagnostics, therapy, and understanding of neurological disease.

Difficulty level: Beginner
Duration: 1:35:08
Speaker: : Petra Ritter

This lesson explains the mathematics of neural mass models and their integration to a coupled network. You will also learn about bifurcation analysis, an important technique in the understanding of non-linear systems and as a fundamental method in the design of brain simulations. Lastly, the application of the described mathematics is demonstrated in the exploration of brain stimulation regimes.

Difficulty level: Beginner
Duration: 1:49:24
Speaker: : Andreas Spiegler

In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.

Difficulty level: Beginner
Duration: 1:28:53
Speaker: : Julie Courtiol

Along the example of a patient with bi-temporal epilepsy, we show step by step how to develop a Virtual Epileptic Patient (VEP) brain model and integrate patient-specific information such as brain connectivity, epileptogenic zone and MRI lesions. The patient's brain network model is then evaluated via simulation, data fitting and mathematical analysis. This lecture demonstrates how to develop novel personalized strategies towards therapy and intervention using TVB.

Difficulty level: Intermediate
Duration: 48:57
Speaker: : Julie Courtiol

This lecture focuses on higher-level simulation scenarios using stimulation protocols. We demonstrate how to build stimulation patterns in TVB, and use them in a simulation to induced activity dissipating into experimentally known resting-state networks in human and mouse brain, a well as to obtain EEG recordings reproducing empirical findings of other researchers.

Difficulty level: Intermediate
Duration: 47:14
Speaker: : Andreas Spiegler