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Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface (GUI). Afterwards, the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.

Difficulty level: Beginner
Duration: 31:22
Speaker: : Paul Triebkorn

This lecture provides an introduction to optogenetics, a biological technique to control the activity of neurons or other cell types with light.

Difficulty level: Beginner
Duration: 39:34
Speaker: : Adam Packer

This tutorial demonstrates how to work with neuronal data using MATLAB, including actional potentials and spike counts, orientation tuing curves in visual cortex, and spatial maps of firing rates.

Difficulty level: Intermediate
Duration: 5:17
Speaker: : Mike X. Cohen

In this lesson, users will learn how to appropriately sort and bin neural spikes, allowing for the generation of a common and powerful visualization tool in neuroscience, the histogram. 

Difficulty level: Intermediate
Duration: 5:31
Speaker: : Mike X. Cohen

Followers of this lesson will learn how to compute, visualize and quantify the tuning curves of individual neurons. 

Difficulty level: Intermediate
Duration: 13:48
Speaker: : Mike X. Cohen

This lesson demonstrates how to programmatically generate a spatial map of neuronal spike counts using MATLAB.

Difficulty level: Intermediate
Duration: 12:16
Speaker: : Mike X. Cohen

In this lesson, users are shown how to create a spatial map of neuronal orientation tuning. 

Difficulty level: Intermediate
Duration: 13:11
Speaker: : Mike X. Cohen

This video will document how to run a correlation analysis between the gray matter volume of two different structures using the output from brainlife app-freesurfer-stats.

Difficulty level: Beginner
Duration: 1:33
Speaker: :

This lesson introduces some practical exercises which accompany the Synapses and Networks portion of this Neuroscience for Machine Learners course. 

Difficulty level: Intermediate
Duration: 3:51
Speaker: : Dan Goodman

This module explores sensation in the brain: what organs are involved, sensory pathways, processing centers, and theories of integration.

Difficulty level: Beginner
Duration: 7:17
Speaker: : Colin Fausnaught

This module covers how the brain interacts with the world through motor movements. Motor movements underlie so much of our functioning, our speech, the opening and closing of our eyes, and the beating of our hearts.

Difficulty level: Beginner
Duration: 5:00
Speaker: : Harrison Canning

This lesson provides an overview of the structure and function of the neuron, its components and mechanisms, action potentials, and the many glial cells that support it.

Difficulty level: Beginner
Duration: 8:31
Speaker: : Colin Fausnaught

This module explains how neurons come together to create the networks that give rise to our thoughts. The totality of our neurons and their connection is called our connectome. Learn how this connectome changes as we learn, and computes information.

Difficulty level: Beginner
Duration: 7:13
Speaker: : Harrison Canning

This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

Difficulty level: Beginner
Duration: 1:16:04

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

Difficulty level: Intermediate
Duration: 1:19:17
Speaker: : Sonny Chen

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Difficulty level: Intermediate
Duration: 1:15:14
Speaker: : Keon Arbabi

This is a tutorial on how to simulate neuronal spiking in brain microcircuit models, as well as how to analyze, plot, and visualize the corresponding data. 

Difficulty level: Intermediate
Duration: 1:39:50
Speaker: : Frank Mazza