In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.
This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases.
This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.
This lesson covers the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication.
In this lesson you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.
This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level.
This lesson covers the spatiotemporal dynamics of the membrane potential.
In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.
This lesson discusses voltage-gating kinetics of sodium and potassium channels.
In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson delves into the specifics of how action potentials propagate through individual neurons.
In this lesson, you will learn about neurotransmitter release in the presynaptic specialization.
This lesson covers synaptic modulation through diffusing neurotransmitters.
This lecture gives an overview of glutamatergic transmission.
This lesson discusses glutamate release after an action potential, and the resulting post-synaptic potentials.
In this lesson, you will learn about glutamatergic excitatory neuronal circuits.
This lesson gives an overview of neurons' dendritic spines and their function.