This tutorial demonstrates how to use the image processing pipeline with the HBP collab.

This tutorial provides instruction on how to use the TVB-NEST toolbox co-simulation in HBP collab.

In this tutorial, you will learn how to use TVB-NEST toolbox on your local computer.

This tutorial provides instruction on how to perform multi-scale simulation of Alzheimer's disease on The Virtual Brain Simulation Platform.

This presentation accompanies the paper entitled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data (see link below to download publication). 

This lesson consists of a supplementary video for the publication: Inferring multi-scale neural mechanisms with brain network modelling.

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

This lecture on model types introduces the advantages of modeling, provide examples of different model types, and explain what modeling is all about. 

This lecture focuses on how to get from a scientific question to a model using concrete examples. We will present a 10-step practical guide on how to succeed in modeling. This lecture contains links to 2 tutorials, lecture/tutorial slides, suggested reading list, and 3 recorded Q&A sessions.

This lecture focuses on the purpose of model fitting, approaches to model fitting, model fitting for linear models, and how to assess the quality and compare model fits. We will present a 10-step practical guide on how to succeed in modeling. 

This lecture provides an overview of the generalized linear models (GLM) course, originally a part of the Neuromatch Academy (NMA), an interactive online summer school held in 2020. NMA provided participants with experiences spanning from hands-on modeling experience to meta-science interpretation skills across just about everything that could reasonably be included in the label "computational neuroscience". 

This lecture introduces the core concepts of dimensionality reduction.

This is the first of a series of tutorials on fitting models to data. In this tutorial, we start with simple linear regression, using least squares optimization.

In this tutorial, we will use a different approach to fit linear models that incorporates the random 'noise' in our data.

This tutorial discusses how to gauge how good our estimated model parameters are.

In this tutorial, we will generalize the regression model to incorporate multiple features.

This tutorial teaches users about the bias-variance tradeoff and see it in action using polynomial regression models.

This tutorial covers how to select an appropriate model based on cross-validation methods. 

This is a tutorial covering Generalized Linear Models (GLMs), which are a fundamental framework for supervised learning. In this tutorial, the objective is to model a retinal ganglion cell spike train by fitting a temporal receptive field: first with a Linear-Gaussian GLM (also known as ordinary least-squares regression model) and then with a Poisson GLM (aka "Linear-Nonlinear-Poisson" model). The data you will be using was published by Uzzell & Chichilnisky 2004.

This tutorial covers the implementation of logistic regression, a special case of GLMs used to model binary outcomes. In this tutorial, we will decode a mouse's left/right decisions from spike train data.