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This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity. 

Difficulty level: Beginner
Duration: 1:22:06
Speaker: : Daniel Buchman

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

Difficulty level: Intermediate
Duration: 1:11:04
Speaker: : Etay Hay

This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.

Difficulty level: Beginner
Duration: 41:00
Speaker: : Dafna Ben Bashat

This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

Difficulty level: Beginner
Duration: 51:49

This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.

Difficulty level: Beginner
Duration: 1:04:04
Speaker: : Bogdan Draganski

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

Difficulty level: Beginner
Duration: 1:29:28

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

Difficulty level: Beginner
Duration: 1:20:28
Speaker: : Abhi Pratap

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

Difficulty level: Beginner
Duration: 45:47

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

Difficulty level: Intermediate
Duration: 1:29:08

In this lesson, you will hear about the current challenges regarding data management, as well as policies and resources aimed to address them. 

Difficulty level: Beginner
Duration: 18:13
Speaker: : Mojib Javadi

This lecture covers the NIDM data format within BIDS to make your datasets more searchable, and how to optimize your dataset searches.

Difficulty level: Beginner
Duration: 12:33
Speaker: : David Keator

This lecture covers positron emission tomography (PET) imaging and the Brain Imaging Data Structure (BIDS), and how they work together within the PET-BIDS standard to make neuroscience more open and FAIR.

Difficulty level: Beginner
Duration: 12:06
Speaker: : Melanie Ganz

This lecture contains an overview of electrophysiology data reuse within the EBRAINS ecosystem.

Difficulty level: Beginner
Duration: 15:57
Speaker: : Andrew Davison

This lecture contains an overview of the Distributed Archives for Neurophysiology Data Integration (DANDI) archive, its ties to FAIR and open-source, integrations with other programs, and upcoming features.

Difficulty level: Beginner
Duration: 13:34

This lecture discusses how to standardize electrophysiology data organization to move towards being more FAIR.

Difficulty level: Beginner
Duration: 15:51